/* ---------------------------------------------------------------------------
 * macrosynteny.css -- 宏共线性三个页面（macrosynteny.php / macrosynteny_result.php
 * / macrosynteny_overview.php）的样式。
 *
 * 配色与控件已统一到站内风格，不再用原来的紫罗兰渐变：
 *   第 1 节 = 站内通用控件（表单 / 按钮 / 表格 / 提示框），类名与 go.php、
 *             kegg.php、interpro.php、proteindomain.php 逐字相同 —— 那几个页面
 *             各自把同一份规则抄在 inline <style> 里，这里集中放一份给本模块的三个页面用。
 *   第 2 节 = 只有本模块用到的东西：Oxford grid 画布、tooltip、连锁群图例、热图色带。
 *
 * 改类名前先看 js/macrosynteny.js，它依赖这些选择器：
 *   #msr-svg / #msr-grid-wrap / #msr-tooltip / #msr-legend / #msr-heatmap ...
 *   .msr-legend .item（.on / .off / .sw）、circle.dim、tr.sel、.msr-tooltip .cl
 * ------------------------------------------------------------------------- */

/* ======================= 1) 站内通用控件 ======================= */

/* 表单容器 */
.kegg-form-container {
    background: #fff;
    border-radius: 12px;
    box-shadow: 0 4px 20px rgba(0, 0, 0, 0.08);
    padding: 35px;
    margin-top: 20px;
    border: 1px solid #e2e8f0;
    max-width: 800px;
    margin-left: auto;
    margin-right: auto;
}
.form-title {
    font-size: 20px;
    font-weight: 600;
    color: #1e293b;
    margin-bottom: 25px;
    display: flex;
    align-items: center;
    gap: 10px;
}
.form-title::before { content: "\1F9EC"; font-size: 24px; }
.form-group { margin-bottom: 25px; }
.form-label {
    display: block;
    font-size: 16px;
    font-weight: 600;
    color: #475569;
    margin-bottom: 10px;
}
.form-select {
    width: 100%;
    padding: 14px 18px;
    border: 2px solid #e2e8f0;
    border-radius: 10px;
    font-size: 16px;
    background: #fff;
    color: #1e293b;
    cursor: pointer;
    transition: all 0.3s ease;
    appearance: none;
    background-image: url("data:image/svg+xml,%3csvg xmlns='http://www.w3.org/2000/svg' fill='none' viewBox='0 0 20 20'%3e%3cpath stroke='%236b7280' stroke-linecap='round' stroke-linejoin='round' stroke-width='1.5' d='M6 8l4 4 4-4'/%3e%3c/svg%3e");
    background-position: right 12px center;
    background-repeat: no-repeat;
    background-size: 20px;
}
.form-select:focus {
    outline: none;
    border-color: #10b981;
    box-shadow: 0 0 0 3px rgba(16, 185, 129, 0.1);
}
.form-select optgroup { font-weight: 700; color: #1e293b; }
.form-select optgroup option { font-weight: 400; color: #1e293b; }

/* 按钮 */
.button-group { display: flex; gap: 15px; margin-top: 30px; }
.btn-submit, .btn-reset {
    flex: 1;
    padding: 14px 30px;
    border-radius: 10px;
    font-size: 16px;
    font-weight: 600;
    cursor: pointer;
    transition: all 0.3s ease;
    display: flex;
    align-items: center;
    justify-content: center;
    gap: 8px;
}
.btn-submit {
    background: linear-gradient(135deg, #10b981 0%, #059669 100%);
    color: #fff;
    border: none;
    box-shadow: 0 4px 12px rgba(16, 185, 129, 0.3);
}
.btn-submit:hover {
    transform: translateY(-2px);
    box-shadow: 0 6px 20px rgba(16, 185, 129, 0.4);
    background: linear-gradient(135deg, #059669 0%, #047857 100%);
}
.btn-reset {
    background: #f8fafc;
    color: #64748b;
    border: 2px solid #e2e8f0;
}
.btn-reset:hover { background: #f1f5f9; color: #475569; border-color: #cbd5e1; }

/* 次级链接（原来用紫色 .msr-btn-ghost，现在统一成站内的绿色文字链接） */
.example-link {
    color: #10b981;
    text-decoration: none;
    font-weight: 600;
    font-size: 14px;
    transition: all 0.3s ease;
    display: inline-flex;
    align-items: center;
    gap: 5px;
    margin-top: 10px;
}
.example-link:hover { color: #059669; text-decoration: underline; }

/* ======================= 2) 本模块专用 ======================= */

/* 页面标题（结果页放 "A vs B"）与统计小药丸 */
.msr-page-title { font-size: 22px; font-weight: 700; color: #1e293b; margin: 0 0 10px; line-height: 1.35; }
.msr-page-title .vs { color: #94a3b8; font-weight: 400; }
.msr-stat {
    display: inline-block; background: #f1f5f9; border: 1px solid #e2e8f0; color: #334155;
    border-radius: 16px; padding: 5px 14px; font-size: 13px; font-weight: 600; margin: 0 8px 8px 0;
}
.msr-stat.green { background: #ecfdf5; border-color: #a7f3d0; color: #047857; }

/* 两列物种选择 */
.msr-two-col { display: grid; grid-template-columns: 1fr 1fr; gap: 18px; }
@media (max-width: 700px) { .msr-two-col { grid-template-columns: 1fr; } }

/* 小字提示 */
.msr-hint { font-size: 13px; color: #94a3b8; margin-top: 8px; line-height: 1.6; }

/* 说明 / 警告框（配色同 genomeinfo.php 的橙色提示条） */
.msr-note {
    background: #f8fafc; border: 1px solid #e2e8f0; border-left: 4px solid #3b82f6;
    border-radius: 10px; padding: 14px 18px; font-size: 14px; color: #334155;
    line-height: 1.75; margin: 18px 0;
}
.msr-note.warn { background: #fffbeb; border-color: #fde68a; border-left-color: #f59e0b; color: #92400e; }
.msr-note code { background: #f1f5f9; padding: 1px 5px; border-radius: 4px; }
.msr-note pre { background: #fff !important; }

/* 小节标题与说明正文 */
.msr-section-title { font-size: 18px; font-weight: 700; color: #1e293b; margin: 28px 0 12px; }
.msr-help { font-size: 13px; color: #64748b; line-height: 1.8; }
.msr-help ul { margin: 8px 0 8px 20px; }

/* ---- 表格：用站内 gridtable，只补上数字右对齐 / 悬停 / 选中 ---- */
table.gridtable td.num { text-align: right; font-variant-numeric: tabular-nums; }
table.gridtable tr:hover td { background: #f8fafc; }
table.gridtable tr.sel td { background: #ecfdf5; }
.msr-table-scroll { max-height: 60vh; overflow: auto; margin: 12px 0; }
#msr-linkage-table { table-layout: auto; }
#msr-linkage-table th { position: sticky; top: 0; z-index: 2; }
.msr-sig { color: #b91c1c; font-weight: 600; }
.msr-ns { color: #94a3b8; }

/* ---- 结果页工具条 ---- */
.msr-toolbar {
    display: flex; flex-wrap: wrap; gap: 10px; align-items: center;
    background: #f8fafc; border: 1px solid #e2e8f0; border-radius: 10px;
    padding: 12px 16px; margin: 16px 0; font-size: 14px; color: #475569;
}
.msr-toolbar label { font-weight: 600; }
.msr-toolbar select, .msr-toolbar input[type=number] {
    padding: 6px 10px; border: 2px solid #e2e8f0; border-radius: 8px; font-size: 14px;
    background: #fff; color: #1e293b;
}
.msr-toolbar select:focus { outline: none; border-color: #10b981; }
.msr-toolbar .example-link { margin-top: 0; }

/* ---- Oxford grid 画布 ---- */
.msr-grid-wrap {
    position: relative; overflow: auto; max-height: 78vh;
    border: 1px solid #e2e8f0; border-radius: 10px; background: #fff;
}
/* 图比容器窄时（适配视图常常如此，因为这张图是方的、容器是宽的）居中放，
   比靠左留一大块空白好看。图比容器宽时 auto 外边距算成 0，不影响滚动。 */
.msr-grid-wrap svg { display: block; margin: 0 auto; cursor: grab; }
.msr-grid-wrap circle { cursor: pointer; }
.msr-grid-wrap circle.dim { opacity: .06; }
.msr-grid-wrap.dragging svg, .msr-grid-wrap.dragging circle { cursor: grabbing; }

/* ---- 全屏：整张图占满窗口（Esc 或左上角小控制条的 ✕ 退出） ---- */
.msr-grid-wrap.msr-full {
    position: fixed; left: 0; top: 0; width: 100%; height: 100%;
    max-height: none; z-index: 5000; border: 0; border-radius: 0;
}
/* 全屏时的浮动控制条。必须是 fixed 且挂在 body 上：容器本身是 overflow:auto 的滚动区，
   放在里面会跟着画布一起滚走。 */
.msr-full-panel {
    position: fixed; left: 12px; top: 12px; z-index: 5001;
    display: flex; gap: 6px; align-items: center;
    background: rgba(255, 255, 255, .95); border: 1px solid #e2e8f0;
    border-radius: 10px; padding: 6px 8px; box-shadow: 0 4px 14px rgba(15, 23, 42, .12);
}

/* ---- tooltip（深色气泡，配色跟随站内 slate） ---- */
.msr-tooltip {
    position: fixed; z-index: 9999; pointer-events: none; display: none;
    background: rgba(15, 23, 42, .96); color: #f8fafc; border-radius: 8px;
    padding: 10px 12px; font-size: 13px; line-height: 1.6; max-width: 460px;
    box-shadow: 0 6px 20px rgba(0, 0, 0, .3);
}
.msr-tooltip b { color: #fff; }
.msr-tooltip a { color: #6ee7b7; }
.msr-tooltip .cl { display: inline-block; width: 10px; height: 10px; border-radius: 2px; margin-right: 6px; }
/* 钉住（单击某个点）之后才接收鼠标事件 —— 里面的基因链接这时才点得到 */
.msr-tooltip.pinned { pointer-events: auto; padding-right: 28px; }
.msr-tooltip .x {
    position: absolute; top: 3px; right: 9px; cursor: pointer;
    color: #94a3b8; font-size: 13px; line-height: 1;
}
.msr-tooltip .x:hover { color: #fff; }

/* ---- 连锁群图例（可点隐藏） ---- */
.msr-legend { display: flex; flex-wrap: wrap; gap: 6px; margin: 12px 0; }
.msr-legend .item {
    display: inline-flex; align-items: center; gap: 6px; font-size: 13px; color: #334155;
    border: 1px solid #e2e8f0; border-radius: 16px; padding: 4px 10px; cursor: pointer;
    background: #fff; user-select: none;
}
.msr-legend .item.on { border-color: #10b981; box-shadow: 0 0 0 2px rgba(16, 185, 129, .15); }
.msr-legend .item.off { opacity: .45; }
.msr-legend .sw { width: 12px; height: 12px; border-radius: 3px; }

/* ---- 概览热图 ---- */
.msr-heat-wrap { overflow: auto; max-height: 82vh; border: 1px solid #e2e8f0; border-radius: 10px; background: #fff; padding: 8px; }
.msr-heat-wrap svg { display: block; }
.msr-heat-legend { display: flex; align-items: center; gap: 10px; font-size: 13px; color: #475569; margin: 10px 0; }
/* 色带对应 js 里默认指标 frac 的绿色 ramp，换默认指标时这里也要跟着改 */
.msr-heat-legend .ramp { width: 180px; height: 12px; border-radius: 6px;
    background: linear-gradient(90deg, #f8fafc 0%, #a7f3d0 35%, #34d399 70%, #047857 100%); }