Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of OS493_005302-T1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of OS493_005302-T1
Gene ID Description PCC Relationship
OS493_005302-T1NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE1positive
OS493_028212-T1GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED0.76positive
OS493_006287-T1UNCHARACTERIZED0.74positive
OS493_005968-T1ALDEHYDE DEHYDROGENASE-RELATED0.72positive
OS493_031326-T1ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD0.72positive
OS493_003203-T1--0.72positive
OS493_029854-T1POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 10.71positive
OS493_034017-T1LACTOYLGLUTATHIONE LYASE GLYOXALASE I0.71positive
OS493_009274-T1GLUTATHIONE GAMMA-GLUTAMYLCYSTEINYLTRANSFERASE0.70positive
OS493_015906-T1NUCLEOPORIN NUP84-RELATED0.70positive
OS493_037978-T1OROTATE PHOSPHORIBOSYLTRANSFERASE0.70positive
OS493_008614-T1-0.70positive
OS493_021812-T1CHOLINE/ETHANOALAMINE KINASE0.69positive
OS493_014736-T1MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 100.69positive
OS493_032440-T1--0.68positive
OS493_012158-T1--0.67positive
OS493_030722-T1WD-REPEAT PROTEIN-RELATED0.67positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 27 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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