Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of OS493_024002-T1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of OS493_024002-T1
Gene ID Description PCC Relationship
OS493_024002-T1N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE1positive
OS493_011165-T1ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED0.86positive
OS493_016338-T1--0.84positive
OS493_033047-T1HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER0.83positive
OS493_005739-T1PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 10.83positive
OS493_028818-T1DYNACTIN SUBUNIT0.82positive
OS493_001794-T1D-ALANYL-D-ALANINE CARBOXYPEPTIDASE0.82positive
OS493_001190-T1N-TERMINAL ACETYLTRANSFERASE-RELATED0.81positive
OS493_032899-T1BRISC AND BRCA1-A COMPLEX MEMBER 20.80positive
OS493_010972-T1CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED0.80positive
OS493_000138-T1URIDINE KINASE0.80positive
OS493_017887-T1POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN0.79positive
OS493_030027-T1CHAPERONIN0.79positive
OS493_021973-T1RIBOSOME BIOGENESIS PROTEIN BRIX0.79positive
OS493_029093-T1ATAXIN 2-BINDING PROTEIN 1-RELATED0.78positive
OS493_002620-T1RAG1-ACTIVATING PROTEIN 10.78positive
OS493_036048-T1PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP50.78positive
OS493_001268-T1OPTICIN0.77positive
OS493_001462-T1PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE0.77positive
OS493_003360-T1LD44762P0.77positive
OS493_039001-T1MINA53 MYC INDUCED NUCLEAR ANTIGEN0.77positive
OS493_029484-T1GLUTATHIONE REDUCTASE0.77positive
OS493_031624-T1TRANSCRIPTION INITIATION FACTOR TFIID0.77positive
OS493_025108-T1--0.76positive
OS493_016920-T1PRESEQUENCE PROTEASE0.76positive
OS493_014877-T1DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE0.76positive
OS493_034166-T1UBIQUITIN-ACTIVATING ENZYME E10.76positive
OS493_015906-T1NUCLEOPORIN NUP84-RELATED0.76positive
OS493_005005-T1M-PHASE PHOSPHOPROTEIN 60.75positive
OS493_009190-T1DUF814-RELATED0.74positive
OS493_028447-T1TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA0.74positive
OS493_021691-T1ERO1-RELATED0.74positive
OS493_012715-T1VESICLE PROTEIN SORTING-ASSOCIATED0.73positive
OS493_006526-T1BETA-ALANINE-ACTIVATING ENZYME0.73positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 76 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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