Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of OS493_024166-T1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of OS493_024166-T1
Gene ID Description PCC Relationship
OS493_024166-T1HOMEOBOX PROTEIN1positive
OS493_007630-T1DRAB5-RELATED0.90positive
OS493_011298-T1CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED0.90positive
OS493_023240-T1--0.90positive
OS493_024925-T1--0.89positive
OS493_018531-T1RUNT RELATED0.87positive
OS493_023241-T1--0.87positive
OS493_036953-T1--0.87positive
OS493_026231-T1--0.87positive
OS493_024254-T1SRCR DOMAIN-CONTAINING PROTEIN0.86positive
OS493_017895-T1ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA0.86positive
OS493_017816-T1--0.86positive
OS493_010468-T1--0.86positive
OS493_017809-T1--0.83positive
OS493_015611-T1IODOTHYRONINE DEIODINASE0.81positive
OS493_024565-T1--0.79positive
OS493_007400-T1--0.78positive
OS493_024170-T1HOMEO BOX HB9 LIKE A-RELATED0.78positive
OS493_039459-T1--0.75positive
OS493_026781-T1FIBRILLIN-RELATED0.70positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 44 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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