Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of OS493_024862-T1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of OS493_024862-T1
Gene ID Description PCC Relationship
OS493_024862-T1NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 131positive
OS493_034988-T1NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B0.97positive
OS493_036810-T1NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED0.96positive
OS493_010098-T1NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 30.96positive
OS493_035603-T1CYTOCHROME C10.96positive
OS493_017210-T1RAB FAMILY0.96positive
OS493_031300-T1TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 80.96positive
OS493_018301-T1NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT0.95positive
OS493_016296-T1NADH DEHYDROGENASE0.95positive
OS493_006466-T1T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN0.95positive
OS493_016396-T1--0.95positive
OS493_036410-T1METHYL-CPG BINDING PROTEIN, MBD0.94positive
OS493_022302-T1RNA BINDING MOTIF RBM PROTEIN -RELATED0.91positive
OS493_010285-T1E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 31 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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