Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of OS493_030175-T1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of OS493_030175-T1
Gene ID Description PCC Relationship
OS493_030175-T1TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 11positive
OS493_038154-T1PROTEIN CBG205670.87positive
OS493_008113-T1SPHINGOMYELIN SYNTHETASE0.86positive
OS493_005960-T1SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS0.86positive
OS493_028994-T1--0.85positive
OS493_027814-T1--0.84positive
OS493_001700-T1--0.84positive
OS493_002638-T1MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN0.84positive
OS493_001697-T1ADHESION G-PROTEIN COUPLED RECEPTOR0.84positive
OS493_039082-T1DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 410.84positive
OS493_036038-T1--0.84positive
OS493_026971-T1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.84positive
OS493_001698-T1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.81positive
OS493_006193-T1TUMOR NECROSIS FACTOR RECEPTOR0.80positive
OS493_014524-T1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED0.79positive
OS493_032048-T1ORGANIC ANION TRANSPORTER0.78positive
OS493_015137-T1--0.77positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 35 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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