Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of OS493_034720-T1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of OS493_034720-T1
Gene ID Description PCC Relationship
OS493_034720-T1DUF614 FAMILY PROTEIN-RELATED1positive
OS493_037082-T1V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A0.86positive
OS493_010220-T1PHOSPHOLIPID SCRAMBLASE-RELATED0.86positive
OS493_015559-T1VACUOLAR SORTING PROTEIN 350.85positive
OS493_023219-T1--0.84positive
OS493_007678-T1LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR0.84positive
OS493_009141-T1UNCHARACTERIZED0.84positive
OS493_009503-T1ADDITIONAL SEX COMBS LIKE PROTEIN ASXL0.84positive
OS493_021130-T1--0.84positive
OS493_030228-T1DEDICATOR OF CYTOKINESIS DOCK0.83positive
OS493_006415-T1MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER0.83positive
OS493_013598-T1EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN0.83positive
OS493_029110-T1SERINE/THREONINE-PROTEIN KINASE 160.83positive
OS493_029119-T1BEIGE/BEACH-RELATED0.82positive
OS493_036211-T1POLYCOMB GROUP PROTEIN0.82positive
OS493_033324-T1SPHINGOSINE KINASE0.82positive
OS493_003652-T1--0.81positive
OS493_039344-T1--0.81positive
OS493_007517-T1LD44762P0.81positive
OS493_024642-T1--0.81positive
OS493_033129-T1BCL-2 RELATED0.80positive
OS493_036736-T1PROTEASE M14 CARBOXYPEPTIDASE0.80positive
OS493_031046-T1--0.80positive
OS493_012622-T1PROPERDIN0.80positive
OS493_005554-T1--0.79positive
OS493_020668-T1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED0.79positive
OS493_009291-T1PROTEIN NIRF0.79positive
OS493_024938-T1--0.79positive
OS493_015418-T1--0.78positive
OS493_014075-T1CDNA SEQUENCE BC0216080.78positive
OS493_005284-T1CALBINDIN0.77positive
OS493_019019-T1ARRESTIN DOMAIN CONTAINING PROTEIN0.76positive
OS493_020514-T1PROLINE AND SERINE-RICH PROTEIN 10.73positive
OS493_005821-T1--0.72positive
OS493_006408-T1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.68positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 88 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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