Co-expression Network Results

Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of XP_001640887.3

Co-expression Network View

Network Legend

Yellow: Query proteins

Green: Interaction proteins

Pink line: Own interaction + positive co-expression

Blue line: Own interaction + negative co-expression

Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.

📋 View Detailed Network Information

Co-expressed Genes of XP_001640887.3

Gene ID	Description	PCC	Relationship
XP_001640887.3	PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED	1	positive
XP_048585600.1	CONDENSIN COMPLEX SUBUNIT 2	0.96	positive
XP_032235309.2	KINETOCHORE PROTEIN NDC80	0.96	positive
XP_032230454.1	CONDENSIN	0.96	positive
XP_032223093.1	HOOK PROTEINS	0.94	positive
XP_001625800.2	CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED	0.94	positive
XP_032221925.2	RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED	0.94	positive
XP_048587352.1	OUTER DENSE FIBER OF SPERM TAILS 2	0.92	positive
XP_032234704.1	SERINE-THREONINE PROTEIN KINASE	0.92	positive
XP_048590162.1	CENTROMERE PROTEIN E	0.91	positive
XP_001626487.2	CYCLINS	0.91	positive
XP_048577409.1	WD REPEAT AND HMG-BOX DNA BINDING PROTEIN	0.91	positive
XP_032221989.2	MYC PROTO-ONCOGENE	0.91	positive
XP_001627379.2	DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN	0.90	positive
XP_032229992.2	PCNA-ASSOCIATED FACTOR	0.90	positive
XP_032231100.2	PROTEIN ECT2	0.90	positive
XP_032239564.2	RHO GTPASE ACTIVATING PROTEIN 11A	0.90	positive
XP_001632005.3	CYCLINS	0.90	positive
XP_001635716.1	NUCLEOLAR AND SPINDLE-ASSOCIATED PROTEIN 1	0.90	positive
XP_001635065.3	HOMEOBOX PROTEIN ARISTALESS	0.89	positive
XP_048585568.1	CONDENSIN COMPLEX SUBUNIT 3-RELATED	0.89	positive
XP_001634378.2	NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A	0.89	positive
XP_048579724.1	PROTEIN HINDERIN	0.89	positive
XP_032218504.1	FLAP ENDONUCLEASE FAMILY MEMBER	0.89	positive
XP_048584606.1	CENTROMERE PROTEIN E	0.89	positive
XP_032241274.2	INNER CENTROMERE PROTEIN	0.88	positive
XP_032237683.2	STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER	0.88	positive
XP_032218171.2	CYTOSKELETON-ASSOCIATED PROTEIN 2-LIKE	0.88	positive
XP_001635865.2	KINETOCHORE PROTEIN SPC25-RELATED	0.88	positive
XP_032218810.2	CMF/LEK/CENP CELL DIVISION-RELATED	0.88	positive
XP_048582498.1	RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN	0.87	positive
XP_032231215.2	WD REPEAT CONTAINING PROTEIN 3 WDR3	0.87	positive
XP_001629476.2	CAMK FAMILY PROTEIN KINASE	0.87	positive
XP_032240895.2	UNCHARACTERIZED	0.87	positive
XP_001638464.1	HISTONE H2B	0.87	positive
XP_001632423.1	CELL DIVISION CYCLE-ASSOCIATED PROTEIN 3	0.86	positive
XP_001625135.2	ADENINE PHOSPHORIBOSYLTRANSFERASE	0.86	positive
XP_032230362.2	CYCLINS	0.84	positive
XP_032225151.2	HISTONE H2B	0.82	positive
XP_032238353.1	--	0.81	positive

Further Analysis for Network Members

Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log₂((mean of group A + 1) / (mean of group B + 1)). This network has 265 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Or take the pairs by hand

XP_032241274.2 XP_001627379.2
XP_001635865.2 XP_001629476.2
XP_001625800.2 XP_032234704.1
XP_032231100.2 XP_032237683.2
XP_001632005.3 XP_001629476.2
XP_032237683.2 XP_048582498.1
XP_001632005.3 XP_001635865.2
XP_032231100.2 XP_048582498.1
XP_032218504.1 XP_048577409.1
XP_032240895.2 XP_001626487.2

Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.