Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of evm.model.Ap9.148
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of evm.model.Ap9.148
Gene ID Description PCC Relationship
evm.model.Ap9.148--1positive
Thr_2486--1.00positive
Thr_2863--1.00positive
Thr_3107--1.00positive
Thr_4008--1.00positive
Thr_885--1.00positive
evm.model.Ap1.1131--1.00positive
evm.model.Ap1.1242--1.00positive
evm.model.Ap1.1910BTB DOMAIN-CONTAINING PROTEIN1.00positive
evm.model.Ap1.1970--1.00positive
evm.model.Ap1.2403BTB/POZ DOMAIN-CONTAINING1.00positive
evm.model.Ap1.2431BTB/POZ DOMAIN-CONTAINING1.00positive
evm.model.Ap1.2554--1.00positive
evm.model.Ap1.2933GLYCOPROTEIN HORMONE RECEPTOR1.00positive
evm.model.Ap1.3095APPLE DOMAIN-CONTAINING PROTEIN1.00positive
evm.model.Ap1.3197HISTONE H41.00positive
evm.model.Ap1.3481RAPSYN-RELATED1.00positive
evm.model.Ap10.1080OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR1.00positive
evm.model.Ap11.439OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR1.00positive
evm.model.Ap11.458RETROTRANSPOSON1.00positive
evm.model.Ap11.494BTB/POZ DOMAIN-CONTAINING1.00positive
evm.model.Ap11.948APPLE DOMAIN-CONTAINING PROTEIN1.00positive
evm.model.Ap12.1561NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR1.00positive
evm.model.Ap12.2286--1.00positive
evm.model.Ap13.149OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR1.00positive
evm.model.Ap14.1695T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN1.00positive
evm.model.Ap14.1792NUCLEOREDOXIN-LIKE PROTEIN 21.00positive
evm.model.Ap2.1988PHOSPHATIDYLSERINE DECARBOXYLASE1.00positive
evm.model.Ap2.3376--1.00positive
evm.model.Ap3.1922OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR1.00positive
evm.model.Ap3.2013DNA HELICASE RECQ FAMILY MEMBER1.00positive
evm.model.Ap4.295OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR1.00positive
evm.model.Ap4.3152THAP DOMAIN PROTEIN1.00positive
evm.model.Ap4.3264--1.00positive
evm.model.Ap4.346--1.00positive
evm.model.Ap4.357--1.00positive
evm.model.Ap4.3580RETROTRANSPOSON1.00positive
evm.model.Ap4.4287--1.00positive
evm.model.Ap4.4393AP ENDONUCLEASE1.00positive
evm.model.Ap4.5526--1.00positive
evm.model.Ap4.6418G PROTEIN-COUPLED RECEPTOR1.00positive
evm.model.Ap4.6552REVERSE TRANSCRIPTASE1.00positive
evm.model.Ap5.2404OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR1.00positive
evm.model.Ap5.2856NECTIN-RELATED1.00positive
evm.model.Ap6.2897BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1.00positive
evm.model.Ap6.2899BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1.00positive
evm.model.Ap6.401--1.00positive
evm.model.Ap6.684ZINC FINGER PROTEIN1.00positive
evm.model.Ap7.1183--1.00positive
evm.model.Ap7.1227EARLY GAMETOCYTE ENRICHED PHOSPHOPROTEIN EGXP1.00positive
evm.model.Ap7.1708RETROTRANSPOSON1.00positive
evm.model.Ap7.2676--1.00positive
evm.model.Ap8.2156C2H2-TYPE DOMAIN-CONTAINING PROTEIN1.00positive
evm.model.Ap8.476F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED1.00positive
evm.model.Ap8.953--1.00positive
evm.model.Ap9.1134SYNDECAN1.00positive
evm.model.Ap9.2312--1.00positive
Gly_428--0.95positive
Thr_3927--0.87positive
evm.model.Ap9.878TRANSPOSASE, PUTATIVE-RELATED0.84positive
evm.model.Ap4.5495--0.78positive
evm.model.Ap14.1726--0.76positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 1828 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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