Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g10214.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g10214.t1
Gene ID Description PCC Relationship
g10214.t1TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED1positive
g27174.t1ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN0.94positive
g8799.t1RAP GTPASE-ACTIVATING PROTEIN0.93positive
g14423.t1VPRBP PROTEIN-RELATED0.93positive
g27898.t1HECT DOMAIN UBIQUITIN-PROTEIN LIGASE0.93positive
g15932.t1--0.93positive
g3151.t1SMC5-SMC6 COMPLEX LOCALIZATION FACTOR 20.93positive
g3152.t1MICROTUBULE-ASSOCIATED PROTEIN 90.92positive
g9749.t1--0.92positive
g4540.t1CALPAIN0.92positive
g4321.t1ADP-RIBOSYLGLYCOHYDROLASE0.92positive
g11669.t1--0.92positive
g23935.t1GLYCOSYLTRANSFERASE 14 FAMILY MEMBER0.92positive
g34960.t1CBF1 INTERACTING COREPRESSOR CIR0.92positive
g12362.t1STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER0.92positive
g6631.t1CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 70.92positive
g25844.t1CARBOHYDRATE SULFOTRANSFERASE0.92positive
g14377.t1NEUROPEPTIDE Y RECEPTOR0.92positive
g35285.t1ATP-DEPENDENT RNA AND DNA HELICASE0.91positive
g20492.t1CYCLIN0.91positive
g25977.t1GLUCOSYLCERAMIDASE0.91positive
g9365.t1SER/THR-RICH PROTEIN T10 IN DGCR REGION0.90positive
g1426.t1NGG1 INTERACTING FACTOR 30.90positive
g7289.t1HEPARANASE0.90positive
g27591.t1SOLUTE CARRIER FAMILY 520.90positive
g8894.t1PRENYLTRANSFERASES0.82positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 101 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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