Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g10331.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g10331.t1
Gene ID Description PCC Relationship
g10331.t1DEUBIQUITINATING PROTEIN VCIP1351positive
g6430.t1SWAP-70 RECOMBINASE0.97positive
g27187.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.97positive
g3404.t1CEREBRAL PROTEIN-11-RELATED0.97positive
g16764.t1YY1 ASSOCIATED PROTEIN-RELATED0.97positive
g16763.t1--0.97positive
g6346.t1MERLIN/MOESIN/EZRIN/RADIXIN0.97positive
g5818.t1CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN0.96positive
g3318.t1--0.96positive
g19648.t1CENTROMERE PROTEIN E0.96positive
g402.t1--0.96positive
g4160.t1--0.96positive
g13812.t1RETINOBLASTOMA BINDING PROTEIN 80.96positive
g10641.t1DYNEIN LIGHT INTERMEDIATE CHAIN0.96positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.96positive
g16204.t1GAMETOGENETIN-BINDING PROTEIN 20.96positive
g27755.t1HOMER0.96positive
g8719.t1QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE0.95positive
g6432.t1SWAP-70 RECOMBINASE0.95positive
g6573.t1--0.95positive
g12882.t1NNMT/PNMT/TEMT FAMILY MEMBER0.95positive
g12187.t1--0.95positive
g27095.t1RIBONUCLEASE0.95positive
g5669.t1ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL0.95positive
g32018.t1--0.95positive
g13588.t1RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR0.95positive
g633.t1MOLTING PROTEIN MLT-40.95positive
g13055.t1AGAP003327-PA0.95positive
g11802.t1--0.95positive
g6427.t1UNCHARACTERIZED0.95positive
g2460.t1PROTEIN CBG124740.95positive
g5251.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.95positive
g9039.t1ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 60.95positive
g24847.t1GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE0.95positive
g3928.t1BEN DOMAIN-CONTAINING PROTEIN 30.95positive
g19976.t1PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 10.95positive
g27405.t1--0.95positive
g3220.t1CEREBLON0.95positive
g27303.t1DYSTROGLYCAN-RELATED0.94positive
g8661.t1TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II0.94positive
g12318.t1CLASP0.94positive
g15206.t1--0.94positive
g32561.t1--0.93positive
g5496.t1HL01030P-RELATED0.92positive
g28201.t1LEUCINE-RICH REPEAT, ISOFORM F-RELATED0.92positive
g21308.t1BONUS, ISOFORM C-RELATED0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 244 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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