Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g10422.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g10422.t1
Gene ID Description PCC Relationship
g10422.t1DNA HELICASE RECQ FAMILY MEMBER1positive
g19552.t1SEC31-RELATED PROTEIN0.90positive
g20801.t1WD REPEAT-CONTAINING PROTEIN 550.89positive
g27949.t1MYOTONIC DYSTROPHY S/T KINASE-RELATED0.88positive
g24048.t1PROTEASOME MATURATION PROTEIN UMP10.86positive
g14202.t1KIAA0586 PROTEIN0.86positive
g2198.t1APOPTOSIS-INDUCING FACTOR 10.86positive
g5379.t1FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN0.86positive
g31982.t1PESCADILLO - RELATED0.85positive
g3015.t1DNA2/NAM7 HELICASE FAMILY MEMBER0.84positive
g34704.t1FERRITIN0.84positive
g30302.t1TOLL-INTERACTING PROTEIN0.84positive
g1466.t1COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR770.83positive
g17342.t1PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED0.82positive
g1544.t126S PROTEASOME REGULATORY SUBUNIT0.82positive
g17854.t150S RIBOSOMAL PROTEIN L210.82positive
g8781.t1CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN0.81positive
g8217.t1UBIQUITIN-ACTIVATING ENZYME E10.81positive
g3217.t1GPALPP MOTIFS-CONTAINING PROTEIN 10.80positive
g2529.t1TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE0.77positive
g19247.t1LYSOPHOSPHOLIPASE-RELATED0.76positive
g71.t1-0.76positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 120 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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