Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g10451.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g10451.t1
Gene ID Description PCC Relationship
g10451.t1WD-40 REPEAT PROTEIN1positive
g10969.t1SAM DOMAIN-CONTAINING PROTEIN-RELATED0.99positive
g8989.t1CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 1570.98positive
g3531.t1ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 120.98positive
g11672.t1TETRATRICOPEPTIDE REPEAT PROTEIN 60.98positive
g35077.t1PAXILLIN-RELATED0.97positive
g18613.t1LEUCINE-RICH REPEAT-CONTAINING PROTEIN 340.97positive
g723.t1ARMADILLO-LIKE HELICAL DOMAIN CONTAINING PROTEIN 10.97positive
g17055.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 400.97positive
g3540.t1UNCHARACTERIZED0.97positive
g7528.t1UNCHARACTERIZED0.97positive
g30241.t1PROTEIN C21ORF590.97positive
g28180.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.97positive
g4155.t1--0.97positive
g9287.t1STI2 PROTEIN-RELATED0.96positive
g5735.t1COILED-COIL DOMAIN-CONTAINING 1660.96positive
g15140.t1NEUROTRANSMITTER GATED ION CHANNEL0.96positive
g2833.t1EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN0.96positive
g7933.t1BRCA1-ASSOCIATED ATM ACTIVATOR 10.96positive
g11673.t1TETRATRICOPEPTIDE REPEAT PROTEIN 60.96positive
g14045.t1-0.96positive
g11591.t1ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED0.95positive
g9566.t1--0.95positive
g10361.t1ANKYRIN REPEAT FAMILY PROTEIN0.95positive
g3302.t1IQ DOMAIN-CONTAINING PROTEIN K0.95positive
g11593.t1--0.95positive
g11592.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.95positive
g6307.t1EPHRIN0.95positive
g29913.t1--0.94positive
g28375.t1TUBULIN POLYGLUTAMYLASE0.94positive
g12445.t1CASPASE-ACTIVATED DNASE0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 160 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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