Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g10484.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g10484.t1
Gene ID Description PCC Relationship
g10484.t15-HYDROXYTRYPTAMINE RECEPTOR1positive
g14626.t1ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA0.99positive
g1988.t1HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g754.t1G PROTEIN-COUPLED RECEPTOR0.99positive
g18961.t1G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER0.99positive
g16163.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g32376.t1LIPOXYGENASE0.99positive
g16328.t1ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g22393.t1SOLUTE CARRIER FAMILY 170.98positive
g11164.t1--0.98positive
g17990.t1--0.98positive
g31897.t1--0.98positive
g19262.t1--0.98positive
g17411.t1PROTEASE M14 CARBOXYPEPTIDASE0.98positive
g5435.t1CARBOHYDRATE SULFOTRANSFERASE0.98positive
g23538.t1--0.98positive
g1846.t1--0.98positive
g8559.t1ZGC:1743560.98positive
g30726.t1--0.98positive
g35343.t1--0.98positive
g10378.t1UNCHARACTERIZED0.98positive
g29517.t1--0.98positive
g21880.t1SUSHI DOMAIN-CONTAINING PROTEIN 10.98positive
g9959.t1TYROSINE-PROTEIN KINASE RECEPTOR0.97positive
g20832.t1MICRO-RNA BINDING ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 70.97positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 64 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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