Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g10641.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g10641.t1
Gene ID Description PCC Relationship
g10641.t1DYNEIN LIGHT INTERMEDIATE CHAIN1positive
g3404.t1CEREBRAL PROTEIN-11-RELATED0.97positive
g13588.t1RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR0.96positive
g19648.t1CENTROMERE PROTEIN E0.96positive
g20120.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.96positive
g10331.t1DEUBIQUITINATING PROTEIN VCIP1350.96positive
g3851.t1SI:DKEY-256H2.10.96positive
g16764.t1YY1 ASSOCIATED PROTEIN-RELATED0.96positive
g16763.t1--0.96positive
g29087.t1AP COMPLEX SUBUNIT MU0.96positive
g27187.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.96positive
g25542.t1RAB GTPASE-ACTIVATING PROTEIN 1-LIKE0.95positive
g11254.t1SPINSTER0.95positive
g4586.t1MATERNAL EFFECT PROTEIN STAUFEN0.95positive
g13129.t1PROTEIN KINASE DOMAIN-CONTAINING PROTEIN0.95positive
g8844.t1KINESIN-LIKE PROTEIN KIN-12D0.95positive
g19336.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.95positive
g22100.t13'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN0.95positive
g8663.t1CASPASE0.95positive
g16204.t1GAMETOGENETIN-BINDING PROTEIN 20.95positive
g5326.t1D-GLUCURONYL C5-EPIMERASE0.95positive
g4496.t1VINCULIN0.95positive
g27303.t1DYSTROGLYCAN-RELATED0.95positive
g572.t1ACTIN0.95positive
g23297.t1PROTEIN DISPATCHED-RELATED0.94positive
g2601.t1SKICH DOMAIN-CONTAINING PROTEIN0.94positive
g8661.t1TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II0.94positive
g27095.t1RIBONUCLEASE0.94positive
g8672.t1CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL0.94positive
g33089.t1DNA2/NAM7 HELICASE FAMILY0.93positive
g6573.t1--0.93positive
g29626.t1KATANIN P80 SUBUNIT0.93positive
g22154.t1N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D10.93positive
g1231.t1--0.93positive
g12495.t1--0.91positive
g34761.t1RAI16 PROTEIN-RELATED0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 179 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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