Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g10648.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g10648.t1
Gene ID Description PCC Relationship
g10648.t1MALE-ENHANCED ANTIGEN-11positive
g27064.t1COPPER TRANSPORT PROTEIN ATOX10.97positive
g20806.t1CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 10.96positive
g20196.t1ENOYL-COA HYDRATASE-RELATED0.96positive
g6805.t1SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 20.96positive
g178.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 250.96positive
g13876.t1ASPARTYL/LYSYL-TRNA SYNTHETASE0.96positive
g17616.t1--0.95positive
g14670.t1NUCLEOPORIN-LIKE PROTEIN 20.95positive
g9218.t1--0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 24 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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