Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g11136.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g11136.t1
Gene ID Description PCC Relationship
g11136.t1ZINC FINGER PROTEIN AEBP21positive
g11201.t1PA-PL1 PHOSPHOLIPASE FAMILY0.98positive
g9758.t1--0.98positive
g17899.t1AGAP011572-PA0.97positive
g28721.t1INTEGRATOR COMPLEX SUBUNIT 20.97positive
g2590.t1LEO1 PROTEIN0.97positive
g20090.t1LD33804P0.97positive
g9206.t1YTH YT521-B HOMOLOGY DOMAIN-CONTAINING0.97positive
g10016.t1NY-REN-41 ANTIGEN L15 -RELATED0.97positive
g2090.t1SIT4 YEAST -ASSOCIATING PROTEIN-RELATED0.96positive
g6007.t1NKAP DOMAIN-CONTAINING 10.96positive
g13577.t1AP COMPLEX SUBUNIT MU0.96positive
g1481.t1PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED0.96positive
g9691.t1NUCLEASE-RELATED0.96positive
g30043.t1SARCOMA ANTIGEN NY-SAR-95-RELATED0.96positive
g5885.t1RIBOSOMAL RNA METHYLTRANSFERASE0.96positive
g34984.t1MYOTUBULARIN-RELATED0.96positive
g12376.t1SENTRIN-SPECIFIC PROTEASE0.96positive
g2481.t1--0.96positive
g11200.t1PA-PL1 PHOSPHOLIPASE FAMILY0.96positive
g870.t1UNCHARACTERIZED0.96positive
g21924.t1RE40534P-RELATED0.96positive
g3004.t1EAP30 SUBUNIT OF ELL COMPLEX0.96positive
g28815.t1ZINC FINGER PROTEIN0.96positive
g14372.t1FIP1-LIKE 1 PROTEIN0.96positive
g5393.t1RUNT RELATED0.96positive
g11975.t1COMPONENT OF OLIGOMERIC GOLGI COMPLEX 60.96positive
g23526.t1--0.96positive
g35422.t1PROTEIN TAG-278-RELATED0.95positive
g6650.t1ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 10.95positive
g6421.t139S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL0.95positive
g12869.t1RIBONUCLEASE0.95positive
g3032.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.95positive
g5352.t1RETINOVIN-RELATED0.95positive
g4776.t1WD REPEAT-CONTAINING PROTEIN 750.95positive
g11417.t1DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS0.95positive
g29750.t1--0.95positive
g5854.t1--0.95positive
g4097.t1--0.95positive
g8668.t1PRE-MRNA-SPLICING FACTOR RBM220.95positive
g112.t1GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 10.95positive
g7286.t1PROTEIN TOPAZ10.95positive
g29564.t1METHYLTRANSFERASE0.94positive
g32113.t1--0.94positive
g6474.t1DIFFERENTIAL DISPLAY AND ACTIVATED BY P53 DDA3 /G2 S PHASE EXPRESSED 10.94positive
g9455.t1--0.94positive
g14884.t1RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 321 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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