Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g112.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g112.t1
Gene ID Description PCC Relationship
g112.t1GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 11positive
g23526.t1--0.96positive
g2481.t1--0.95positive
g8571.t1DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN0.95positive
g6650.t1ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 10.95positive
g13577.t1AP COMPLEX SUBUNIT MU0.95positive
g21924.t1RE40534P-RELATED0.95positive
g11136.t1ZINC FINGER PROTEIN AEBP20.95positive
g12316.t1CLASP0.95positive
g4097.t1--0.95positive
g28623.t1SERINE/THREONINE-PROTEIN KINASE TAO0.94positive
g28721.t1INTEGRATOR COMPLEX SUBUNIT 20.94positive
g6277.t1THUMP DOMAIN CONTAINING PROTEIN 1-RELATED0.94positive
g6421.t139S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL0.94positive
g18362.t1AGAP011099-PA0.94positive
g3032.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.94positive
g10632.t1XYLOSYLTRANSFERASE OXT0.94positive
g6839.t1--0.94positive
g12376.t1SENTRIN-SPECIFIC PROTEASE0.94positive
g29356.t1S-ADENOSYL-METHYLTRANSFERASE MRAW0.94positive
g13243.t1ATP-BINDING CASSETTE SUB-FAMILY C0.94positive
g29564.t1METHYLTRANSFERASE0.93positive
g16888.t1TRANSCRIPTIONAL REPRESSOR P66-RELATED0.93positive
g27537.t1--0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 113 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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