Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g11290.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g11290.t1
Gene ID Description PCC Relationship
g11290.t1-1positive
g18162.t1VILLIN0.81positive
g23773.t1RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D0.81positive
g11685.t1KU AUTOANTIGEN DNA HELICASE0.79positive
g2985.t1--0.79positive
g637.t11-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE0.78positive
g11913.t1IMPORTIN-7, 8, 110.77positive
g17207.t1BLUE CHEESE0.76positive
g11621.t1NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG0.76positive
g7932.t1-0.76positive
g12377.t1METABOTROPIC GLUTAMATE RECEPTOR0.75positive
g35569.t1ZINC METALLOPROTEINASE-RELATED0.75positive
g32423.t1HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED0.74positive
g2697.t1LYSOSOMAL COBALAMIN TRANSPORTER-RELATED0.74positive
g7724.t1N-ACETYLGLUCOSAMINYLTRANSFERASE VI0.74positive
g14401.t1INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG0.74positive
g21736.t1PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN0.74positive
g5479.t1SERINE PROTEASE INHIBITOR0.73positive
g25483.t1GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 10.73positive
g5817.t1ORIGIN RECOGNITION COMPLEX SUBUNIT 20.73positive
g3678.t1LAR INTERACTING PROTEIN LIP -RELATED PROTEIN0.73positive
g5489.t1TRANSCRIPTASE, PUTATIVE-RELATED-RELATED0.72positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 61 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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