Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g11408.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g11408.t1
Gene ID Description PCC Relationship
g11408.t1--1positive
g27269.t1ZINC FINGER PROTEIN0.94positive
g20136.t1PHEROMONE SHUTDOWN PROTEIN0.93positive
g11282.t1MAP KINASE KINASE KINASE SSK2-RELATED-RELATED0.93positive
g35378.t1--0.93positive
g4161.t1MULTICOPPER OXIDASE-RELATED0.93positive
g27687.t1DNAJ HOMOLOG SUBFAMILY C MEMBER 170.93positive
g16919.t1ES-2 PROTEIN - RELATED0.93positive
g7431.t1--0.93positive
g10316.t1--0.92positive
g11437.t1AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 20.92positive
g12233.t1--0.92positive
g14967.t1MRNA-CAPPING ENZYME0.92positive
g109.t1PDZ AND LIM DOMAIN PROTEIN ZASP0.91positive
g7287.t1--0.91positive
g9406.t1KINESIN-RELATED0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 50 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP