Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g12003.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g12003.t1
Gene ID Description PCC Relationship
g12003.t1--1positive
g1428.t1BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR0.98positive
g24142.t1X-BOX BINDING PROTEIN 10.97positive
g5613.t1AMMONIUM TRANSPORTER0.97positive
g2504.t1SLR5058 PROTEIN0.97positive
g619.t1-0.97positive
g36640.t1SYNAPTOTAGMIN 14, ISOFORM D0.97positive
g2934.t1ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE0.97positive
g2955.t1ASPARTYL PROTEASE-RELATED0.97positive
g22702.t1SOLUTE CARRIER FAMILY 350.97positive
g11655.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 120.97positive
g23789.t1MALATE SYNTHASE0.97positive
g27347.t1PROTEIN CBG162000.97positive
g5927.t1ALPHA-L-FUCOSIDASE0.97positive
g467.t1TRANSCRIPTION TERMINATION FACTOR 2-RELATED0.96positive
g18267.t1TRANSCRIPTION ELONGATION FACTOR SPT60.96positive
g13404.t1FORKHEAD BOX PROTEIN O0.96positive
g12274.t1ATP-CITRATE SYNTHASE0.96positive
g993.t1ADENOSINE/GUANOSINE DIPHOSPHATASE0.96positive
g1197.t1DOUBLE-STRAND BREAK REPAIR RAD50 ATPASE, PUTATIVE-RELATED0.96positive
g16765.t1PHOSPHATIDYLCHOLINE TRANSFER PROTEIN0.96positive
g33056.t1ALPHA KINASE/ELONGATION FACTOR 2 KINASE0.96positive
g581.t1BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 10.96positive
g5040.t1UNCHARACTERIZED0.96positive
g12303.t1DOPAMINE BETA HYDROXYLASE RELATED0.96positive
g3327.t1-0.96positive
g6321.t1PROTEASE M14 CARBOXYPEPTIDASE0.96positive
g21652.t1P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE0.96positive
g5329.t1SYNAPTOTAGMIN 14, ISOFORM D0.96positive
g7130.t1PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN0.96positive
g10464.t1LD33804P0.95positive
g2885.t1TYROSINE-PROTEIN KINASE0.95positive
g29909.t1--0.95positive
g11024.t1CALSYNTENIN0.95positive
g16483.t1--0.95positive
g25794.t1TRANSPOSASE, PUTATIVE-RELATED0.95positive
g23578.t1-0.95positive
g31262.t1--0.95positive
g25391.t1EXPRESSED PROTEIN0.95positive
g7918.t1MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN0.95positive
g8806.t1RETROTRANSPOSON0.95positive
g18662.t1MAINTENANCE OF TELOMOERE CAPPING0.94positive
g10069.t1--0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 274 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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