Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g12410.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g12410.t1
Gene ID Description PCC Relationship
g12410.t1NADP-SPECIFIC GLUTAMATE DEHYDROGENASE 1-RELATED1positive
g2947.t1DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN0.96positive
g33287.t1DYNEIN HEAVY CHAIN0.96positive
g3329.t1SOLUTE CARRIER FAMILY 22 MEMBER0.95positive
g516.t1NEPHROCYSTIN0.95positive
g10208.t1CORTACTIN AND DREBRIN0.95positive
g16087.t1MACROGLOBULIN / COMPLEMENT0.95positive
g14709.t1ADIPOLIN0.95positive
g5743.t1UNC-13-4A, ISOFORM B0.94positive
g4078.t1O-METHYLTRANSFERASE-RELATED0.94positive
g6364.t1GROWTH FACTOR RECEPTOR-BOUND PROTEIN0.94positive
g11061.t1--0.93positive
g4960.t1PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN0.93positive
g15751.t1UNCHARACTERIZED0.93positive
g1099.t1UNCHARACTERIZED0.93positive
g26208.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 890.92positive
g12412.t1ACYL-COA SYNTHETASE0.92positive
g28887.t1GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT0.92positive
g10512.t1ARGININOSUCCINATE LYASE0.92positive
g5965.t1--0.84positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 71 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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