Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g1295.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g1295.t1
Gene ID Description PCC Relationship
g1295.t1DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 11positive
g23976.t1SODIUM/CALCIUM EXCHANGER0.95positive
g34144.t1BLOC-1-RELATED COMPLEX SUBUNIT 50.94positive
g10554.t1OS02G0815200 PROTEIN0.94positive
g6125.t1--0.94positive
g4897.t1CRUMBS FAMILY MEMBER0.93positive
g6655.t1FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER0.93positive
g509.t1AMINOMETHYLTRANSFERASE0.93positive
g9960.t1EPH RECEPTOR A50.93positive
g28015.t1RHO FAMILY GTPASE0.93positive
g7212.t1RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN0.92positive
g9464.t1CADHERIN-230.92positive
g6476.t1PHD/F-BOX CONTAINING PROTEIN0.92positive
g1170.t1TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II0.92positive
g28073.t1GLYCINE N-METHYLTRANSFERASE0.92positive
g5324.t1PX DOMAIN-CONTAINING PROTEIN0.92positive
g15001.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.91positive
g28086.t1DNAJ HOMOLOG SUBFAMILY B MEMBER 20.91positive
g8048.t1SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS0.91positive
g33984.t1--0.91positive
g27667.t1--0.91positive
g5323.t1MULTICOPPER OXIDASE-RELATED0.90positive
g13656.t1NUCLEOBINDIN0.90positive
g3983.t1KELCH PROTEIN0.90positive
g36531.t1SIMILAR TO RIKEN CDNA E130308A190.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 124 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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