Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g12975.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g12975.t1
Gene ID Description PCC Relationship
g12975.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED1positive
g15093.t1NETRIN/LAMININ-RELATED0.95positive
g6524.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.94positive
g6502.t1CCCH ZINC FINGER/TIS11-RELATED0.94positive
g7773.t1TYROSINE-PROTEIN KINASE RECEPTOR0.93positive
g444.t1PR DOMAIN ZINC FINGER PROTEIN0.93positive
g34939.t1TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS0.93positive
g31790.t1--0.93positive
g32564.t1RETROTRANSPOSON0.92positive
g9804.t1STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE0.91positive
g474.t1SYNAPTOTAGMIN0.91positive
g10773.t1--0.91positive
g23376.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.90positive
g26448.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.90positive
g27833.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.88positive
g17420.t1--0.87positive
g5332.t1PROTEIN CBG266940.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 41 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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