Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g13447.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g13447.t1
Gene ID Description PCC Relationship
g13447.t1YNEIN REGULATORY COMPLEX SUBUNIT 51positive
g15827.t160S RIBOSOMAL PROTEIN L3-RELATED0.98positive
g27318.t1LIPOXYGENASE0.98positive
g8779.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.98positive
g2576.t1DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED0.98positive
g15700.t1CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 40.98positive
g18803.t1--0.98positive
g3104.t1ANK_REP_REGION DOMAIN-CONTAINING PROTEIN0.98positive
g19031.t1--0.98positive
g7156.t1GLYCOPROTEIN HORMONE RECEPTOR0.98positive
g26124.t1--0.98positive
g31836.t1PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN0.97positive
g7849.t1PROTEIN CBG266940.96positive
g17627.t1SI:CH211-108C17.2-RELATED-RELATED0.96positive
g33818.t1--0.96positive
g19637.t1ANKYRIN REPEAT FAMILY PROTEIN0.96positive
g22499.t1PROTEIN CBG266940.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 41 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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