Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g1399.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g1399.t1
Gene ID Description PCC Relationship
g1399.t1TGF-BETA FAMILY1positive
g5047.t1C2H2 ZINC FINGER CGI-62-RELATED0.92positive
g3207.t1--0.90positive
g3898.t1MDM2-BINDING PROTEIN0.88positive
g13387.t1ATF6, ISOFORM C0.88positive
g4966.t1PARKIN COREGULATED GENE PROTEIN PARK2 COREGULATED0.87positive
g17456.t1BCS1 AAA-TYPE ATPASE0.86positive
g9920.t1--0.86positive
g12729.t1FANCONI ANEMIA GROUP F PROTEIN FANCF0.85positive
g1840.t1ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV0.85positive
g9919.t1SOLUTE CARRIER FAMILY 250.85positive
g2523.t1MRNA EXPORT FACTOR AND BUB30.85positive
g30567.t1BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED0.85positive
g14086.t1HEPARAN SULFATE 2-O-SULFOTRANSFERASE0.85positive
g7922.t1RP42 RELATED0.84positive
g27813.t1E3 UBIQUITIN-PROTEIN LIGASE TRIM370.84positive
g6235.t1FASCIN0.84positive
g6221.t1CENTROSOMAL PROTEIN OF 131 KDA0.82positive
g6214.t1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED0.82positive
g12236.t1MEMBRANE-SPANNING 4-DOMAINS SUBFAMILY A MS4A -RELATED0.82positive
g8895.t1CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS0.82positive
g12631.t1--0.81positive
g4694.t1FUKUTIN RELATED PROTEIN0.80positive
g20902.t1LD44762P0.80positive
g10724.t1METHYLENETETRAHYDROFOLATE REDUCTASE0.80positive
g32809.t1DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 120.80positive
g30239.t1PROTEIN DD3-30.77positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 135 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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