Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g14109.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g14109.t1
Gene ID Description PCC Relationship
g14109.t1BTB/POZ DOMAIN-CONTAINING1positive
g7607.t1UNCHARACTERIZED0.95positive
g1411.t1DNA HELICASE RECQ FAMILY MEMBER0.92positive
g10103.t1--0.92positive
g3304.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.92positive
g1013.t1E3 UBIQUITIN-PROTEIN LIGASE TTC30.91positive
g27513.t1GLUCONOKINASE-RELATED0.91positive
g28728.t1AP ENDONUCLEASE0.91positive
g33745.t1ANKYRIN REPEAT PROTEIN0.91positive
g29582.t1UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN0.90positive
g28922.t1--0.90positive
g11549.t1UBIQUITIN THIOESTERASE0.90positive
g27915.t1IRE1-RELATED0.90positive
g5729.t1WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED0.90positive
g27371.t1SEC14 RELATED PROTEIN0.90positive
g3982.t1PROTEIN DD3-30.90positive
g27760.t1--0.87positive
g33872.t1PEROXISOMAL BIOGENESIS FACTOR 30.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 50 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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