Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g14361.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g14361.t1
Gene ID Description PCC Relationship
g14361.t1--1positive
g30407.t1RHO-GTPASE-ACTIVATING PROTEIN LRG10.96positive
g28515.t1--0.96positive
g4793.t1EGF-LIKE DOMAIN-CONTAINING PROTEIN0.95positive
g782.t1RETINOBLASTOMA-BINDING PROTEIN 50.95positive
g5591.t1HEXAMETHYLENE BISACETAMIDE INDUCIBLE 10.95positive
g7777.t1SPROUTY0.95positive
g9174.t1SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 10.95positive
g28030.t1POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED0.95positive
g17518.t1DRAB5-RELATED0.95positive
g8210.t1--0.95positive
g10326.t1MYOSIN REGULATORY LIGHT CHAIN 20.95positive
g30795.t1--0.94positive
g15318.t1--0.94positive
g16155.t1--0.94positive
g29393.t1UNCHARACTERIZED0.93positive
g13400.t1KERATIN, ULTRA HIGH-SULFUR MATRIX PROTEIN-LIKE0.93positive
g29398.t1DNA HELICASE RECQ FAMILY MEMBER0.91positive
g26222.t1OLFACTOMEDIN-RELATED0.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 60 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP