Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g1437.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g1437.t1
Gene ID Description PCC Relationship
g1437.t139A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL1positive
g9735.t1ATAXIN-3-RELATED0.98positive
g14416.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 580.98positive
g16207.t1PROTEIN CBG266940.98positive
g7398.t1TYROSINE AMINOTRANSFERASE0.98positive
g17935.t1NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-10.98positive
g5709.t1KUNITZ-TYPE PROTEASE INHIBITOR-RELATED0.98positive
g2452.t1GOLGI SNARE BET1-RELATED0.98positive
g1064.t1MICROSOMAL PROSTAGLANDIN E SYNTHASE-20.98positive
g9895.t1MITOCHONDRIAL RIBOSOMAL PROTEIN S250.98positive
g14839.t1LIPASE0.97positive
g16977.t1SEL-1-LIKE PROTEIN0.97positive
g10551.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED0.97positive
g9808.t1LYMPHOID-SPECIFIC HELICASE0.97positive
g5552.t1MINA53 MYC INDUCED NUCLEAR ANTIGEN0.97positive
g8443.t1IMPORTIN ALPHA0.97positive
g29628.t1EME1 PROTEIN0.97positive
g21678.t1DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED0.97positive
g366.t1KINETOCHORE-ASSOCIATED PROTEIN NSL1 HOMOLOG0.97positive
g29028.t1TTC17 PROTEIN0.97positive
g27348.t1--0.97positive
g6693.t1UPF0598 PROTEIN C8ORF820.97positive
g22364.t1SIKE FAMILY MEMBER0.97positive
g21234.t1MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 100.97positive
g14958.t1TOUCAN, ISOFORM A0.97positive
g352.t1--0.97positive
g5002.t1SUGAR KINASE0.96positive
g11993.t1NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT0.96positive
g6310.t1L-THREONINE 3-DEHYDROGENASE0.96positive
g20963.t1--0.95positive
g15970.t1TROPONIN C-AKIN-1 PROTEIN0.95positive
g16173.t1HISTIDINE TRIAD HIT PROTEIN0.95positive
g10196.t1PREFOLDIN SUBUNIT 30.95positive
g30363.t1OVOCHYMASE-RELATED0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 197 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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