Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g14669.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g14669.t1
Gene ID Description PCC Relationship
g14669.t1COLLAGEN ALPHA1positive
g25713.t1--1.00positive
g17124.t1EGF-LIKE DOMAIN-CONTAINING PROTEIN1.00positive
g4327.t1TYROSINE-PROTEIN KINASE RECEPTOR0.99positive
g6445.t1FIBRILLIN-RELATED0.99positive
g192.t1COLLAGEN ALPHA0.99positive
g520.t1VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED0.99positive
g27514.t1TRANSLATION ELONGATION FACTOR-RELATED0.99positive
g7800.t1GLUTAMATE SEMIALDEHYDE DEHYDROGENASE0.99positive
g7283.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g7.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g6446.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.99positive
g24840.t1--0.99positive
g21670.t1MACROGLOBULIN / COMPLEMENT0.99positive
g35342.t1BRORIN FAMILY MEMBER0.99positive
g19554.t1NG370.99positive
g7527.t1--0.99positive
g13535.t1SODIUM/CALCIUM EXCHANGER0.99positive
g27985.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.99positive
g4326.t1FIBROBLAST GROWTH FACTOR RECEPTOR0.99positive
g27623.t1SERINE PROTEASE0.99positive
g28228.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g27051.t1--0.99positive
g28150.t1--0.99positive
g16491.t1NADH-CYTOCHROME B5 REDUCTASE0.99positive
g15256.t1COLLAGEN ALPHA0.99positive
g15208.t1TYROSINE-PROTEIN KINASE RECEPTOR0.99positive
g30478.t1--0.99positive
g2069.t1COLLAGEN ALPHA0.99positive
g113.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.99positive
g33383.t1IP13529P0.99positive
g16169.t1--0.99positive
g7074.t1IDURONATE 2-SULFATASE0.99positive
g14023.t1LYSYL OXIDASE-LIKE-RELATED0.99positive
g31620.t1CONTACTIN 50.99positive
g14393.t1COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING0.99positive
g26571.t1--0.99positive
g15612.t1T-BOX PROTEIN-RELATED0.99positive
g31641.t152 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED0.99positive
g14432.t1SRCR DOMAIN-CONTAINING PROTEIN0.99positive
g8155.t1L-FUCOSE KINASE0.98positive
g15978.t1SI:DKEY-256H2.10.98positive
g1531.t1--0.98positive
g6965.t1--0.98positive
g28496.t1LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED0.98positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 287 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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