Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g1478.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g1478.t1
Gene ID Description PCC Relationship
g1478.t1--1positive
g16195.t1BTB/POZ DOMAIN-CONTAINING0.98positive
g10016.t1NY-REN-41 ANTIGEN L15 -RELATED0.98positive
g2090.t1SIT4 YEAST -ASSOCIATING PROTEIN-RELATED0.98positive
g16665.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.98positive
g13660.t1METHYLTRANSFERASE0.97positive
g28257.t1PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED0.97positive
g21084.t1TRANSLATION FACTOR GUF1-RELATED0.97positive
g2998.t1ENHANCER OF POLYCOMB0.97positive
g5958.t1XPA-BINDING PROTEIN 1-RELATED0.97positive
g28024.t1HSC70CB, ISOFORM G-RELATED0.97positive
g3739.t1PROLINE-RICH NUCLEAR RECEPTOR COACTIVATOR0.97positive
g5767.t1UNCHARACTERIZED0.97positive
g22059.t1--0.97positive
g2568.t1--0.97positive
g8339.t1--0.97positive
g5353.t1SERINE/THREONINE-PROTEIN KINASE RIO10.97positive
g20604.t1SPOT14 FAMILY MEMBER0.96positive
g9302.t1RING ZINC FINGER PROTEIN0.96positive
g27270.t1BOULE-RELATED0.96positive
g11704.t1PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE0.96positive
g5352.t1RETINOVIN-RELATED0.96positive
g31850.t1CENTROSOMAL PROTEIN OF 162 KDA0.96positive
g3032.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.96positive
g14208.t1LOQUACIOUS, ISOFORM B0.96positive
g28815.t1ZINC FINGER PROTEIN0.96positive
g6584.t1GATA-TYPE ZINC FINGER PROTEIN 10.96positive
g3656.t1--0.96positive
g19527.t1POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED0.96positive
g1243.t1TOLL-LIKE RECEPTOR0.96positive
g28727.t1UBIQUITIN CARBOXYL-TERMINAL HYDROLASE0.95positive
g1679.t1BETA-HEXOSAMINIDASE0.95positive
g5854.t1--0.95positive
g10333.t1HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.95positive
g9788.t1--0.95positive
g26215.t1--0.95positive
g29564.t1METHYLTRANSFERASE0.95positive
g32455.t1--0.94positive
g30521.t1--0.94positive
g4495.t1--0.94positive
g28274.t1--0.94positive
g19593.t1SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER0.94positive
g12783.t1--0.93positive
g31818.t1LEUCOKININ RECEPTOR-RELATED0.93positive
g31308.t1--0.89positive
g4072.t1G PROTEIN-COUPLED RECEPTOR 157-RELATED0.86positive
g18116.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.83positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 318 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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