Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g15001.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g15001.t1
Gene ID Description PCC Relationship
g15001.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED1positive
g9464.t1CADHERIN-230.94positive
g23806.t1VOLTAGE-GATED POTASSIUM CHANNEL0.94positive
g6476.t1PHD/F-BOX CONTAINING PROTEIN0.94positive
g3205.t1TRANSCRIPTIONAL ADAPTER 3-RELATED0.94positive
g28015.t1RHO FAMILY GTPASE0.94positive
g2178.t1--0.93positive
g7818.t1CYTOKINESIS PROTEIN 30.92positive
g4897.t1CRUMBS FAMILY MEMBER0.92positive
g560.t1--0.91positive
g1295.t1DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 10.91positive
g36181.t1--0.91positive
g28086.t1DNAJ HOMOLOG SUBFAMILY B MEMBER 20.91positive
g19656.t1TRANSCRIPTION FACTOR CP20.90positive
g23832.t1TRANSPOSABLE ELEMENT-RELATED0.89positive
g11439.t1--0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 54 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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