Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g15364.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g15364.t1
Gene ID Description PCC Relationship
g15364.t1ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC91positive
g810.t1CENTROMERE/MICROTUBULE BINDING PROTEIN CBF50.99positive
g15722.t1--0.98positive
g20374.t1ATP-DEPENDENT RNA HELICASE0.98positive
g9361.t1DNA POLYMERASE DELTA SUBUNIT 40.97positive
g11185.t1MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED0.97positive
g30449.t1TRANSLATION FACTOR0.97positive
g4232.t1CAT EYE SYNDROME CRITICAL REGION PROTEIN 60.97positive
g34957.t1--0.97positive
g3267.t1ADP RIBOSYLATION FACTOR-RELATED0.97positive
g16715.t1NAZO FAMILY MEMBER0.97positive
g845.t1BYSTIN0.96positive
g12385.t1OXIDATIVE STRESS-RESPONSE SERINE-RICH PROTEIN 10.96positive
g10221.t1TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER0.96positive
g17465.t1BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED0.96positive
g439.t1PR DOMAIN ZINC FINGER PROTEIN0.95positive
g27698.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.95positive
g34723.t1GLUTATHIONE PEROXIDASE0.95positive
g11305.t1THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING0.95positive
g27230.t1PEPTIDYL-TRNA HYDROLASE0.95positive
g5939.t1RIBOSOMAL PROTEIN L7AE FAMILY MEMBER0.94positive
g2706.t1--0.94positive
g19811.t1GLOMULIN0.94positive
g9312.t1ERO1-RELATED0.94positive
g24108.t1--0.94positive
g9754.t1--0.94positive
g33690.t1HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN0.94positive
g23284.t1DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN0.94positive
g20281.t1HOMEOBOX PROTEIN0.94positive
g2695.t1--0.94positive
g19899.t1--0.93positive
g13671.t1SI:CH211-108C17.2-RELATED-RELATED0.93positive
g25865.t1ARGININE OR CREATINE KINASE0.93positive
g8957.t1--0.93positive
g6831.t1TRIHELIX TRANSCRIPTION FACTOR ASIL20.93positive
g11418.t1PETER PAN-RELATED0.93positive
g493.t1NUCLEAR HORMONE RECEPTOR0.93positive
g8539.t1FI14130P0.92positive
g32853.t1--0.90positive
g16105.t1--0.89positive
g4669.t1--0.89positive
g31341.t1--0.86positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 250 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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