Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g15438.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g15438.t1
Gene ID Description PCC Relationship
g15438.t1--1positive
g8733.t1CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN0.99positive
g13454.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g10390.t1--0.99positive
g4784.t1POLYCYSTIN FAMILY MEMBER0.99positive
g10513.t1REVERSE TRANSCRIPTASE0.99positive
g1558.t1--0.99positive
g2113.t1--0.99positive
g27238.t1TRYPTASE-RELATED0.99positive
g6303.t1XANTHINE DEHYDROGENASE0.99positive
g7.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g13536.t1SODIUM/CALCIUM EXCHANGER0.99positive
g4797.t1POLYCYSTIN-10.99positive
g4688.t1OVOCHYMASE-RELATED0.99positive
g2901.t1ANKYRIN REPEAT PROTEIN0.99positive
g6445.t1FIBRILLIN-RELATED0.98positive
g853.t1--0.98positive
g15548.t1--0.98positive
g14447.t1MONOCARBOXYLATE TRANSPORTER0.98positive
g10568.t1SODIUM/CHLORIDE DEPENDENT TRANSPORTER0.98positive
g7699.t1--0.98positive
g22650.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.98positive
g24682.t1--0.98positive
g25328.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.98positive
g21133.t1--0.97positive
g9689.t1--0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 85 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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