Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g15495.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g15495.t1
Gene ID Description PCC Relationship
g15495.t1CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED1positive
g14627.t1ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA0.99positive
g7283.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g12614.t1BONUS, ISOFORM C-RELATED0.99positive
g2538.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g27014.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g16164.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g7.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g19151.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g16163.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g4220.t1CYSTEINE-RICH SECRETORY PROTEIN-RELATED0.99positive
g6876.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.99positive
g1938.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED0.99positive
g4058.t1ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED0.99positive
g3962.t1VERY KIND PROTEIN0.99positive
g6416.t1--0.99positive
g4014.t1GUANYLYL CYCLASE0.98positive
g7913.t1SYNAPSIN0.98positive
g11798.t1CUB DOMAIN-CONTAINING PROTEIN0.98positive
g1102.t1VOLTAGE-GATED POTASSIUM CHANNEL0.98positive
g16088.t1PROTEIN CBG053490.98positive
g2539.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.98positive
g2953.t1VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 80.97positive
g5742.t1UNC-13-4A, ISOFORM B0.96positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 112 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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