Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g15545.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g15545.t1
Gene ID Description PCC Relationship
g15545.t1--1positive
g18961.t1G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER1.00positive
g3335.t1--1.00positive
g14918.t1TRYPSIN-RELATED0.99positive
g528.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.99positive
g10112.t1CENTROSOMAL PROTEIN 20.99positive
g3612.t1--0.99positive
g16833.t1EGF-LIKE DOMAIN-CONTAINING PROTEIN0.99positive
g9610.t1--0.99positive
g26779.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g3364.t1GUANYLYL CYCLASE0.99positive
g27945.t1--0.99positive
g11133.t1CUB DOMAIN-CONTAINING PROTEIN0.99positive
g18966.t1LEUCOKININ RECEPTOR-RELATED0.99positive
g17556.t1CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE0.99positive
g23746.t1--0.99positive
g5016.t1ADENYLATE CYCLASE TYPE 10.99positive
g1319.t1--0.99positive
g31603.t1--0.99positive
g7333.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.99positive
g20228.t1SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS0.99positive
g14893.t1PROTEIN CBR-CLEC-780.99positive
g35342.t1BRORIN FAMILY MEMBER0.99positive
g627.t1--0.99positive
g10672.t1--0.99positive
g16902.t1IONOTROPIC GLUTAMATE RECEPTOR0.99positive
g7147.t1KREMEN PROTEIN0.99positive
g4055.t1--0.99positive
g23600.t1G PROTEIN-COUPLED RECEPTOR0.99positive
g5258.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g32539.t1--0.99positive
g2117.t1--0.99positive
g14626.t1ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA0.99positive
g11099.t1--0.99positive
g18965.t1CARBOHYDRATE SULFOTRANSFERASE0.99positive
g27708.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g3365.t1--0.99positive
g29586.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g29047.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g4437.t1--0.99positive
g28709.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.99positive
g12977.t1--0.99positive
g6365.t1LANC-LIKE PROTEIN0.99positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 252 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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