Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g15797.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g15797.t1
Gene ID Description PCC Relationship
g15797.t1UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN1positive
g14208.t1LOQUACIOUS, ISOFORM B0.98positive
g17153.t1M-PHASE PHOSPHOPROTEIN 60.98positive
g9742.t1ATP-DEPENDENT RNA HELICASE0.97positive
g11975.t1COMPONENT OF OLIGOMERIC GOLGI COMPLEX 60.97positive
g2090.t1SIT4 YEAST -ASSOCIATING PROTEIN-RELATED0.97positive
g9302.t1RING ZINC FINGER PROTEIN0.97positive
g5353.t1SERINE/THREONINE-PROTEIN KINASE RIO10.97positive
g8171.t1UNCHARACTERIZED0.97positive
g20917.t1MED-6-RELATED0.97positive
g6204.t1OLIGOPHRENIN 10.97positive
g15431.t1GOS-28 SNARE- RELATED0.97positive
g3656.t1--0.97positive
g10016.t1NY-REN-41 ANTIGEN L15 -RELATED0.97positive
g5631.t1GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-20.96positive
g9195.t1RGS-GAIP INTERACTING PROTEIN GIPC0.96positive
g4222.t1KELCH DOMAIN-CONTAINING PROTEIN 100.96positive
g5885.t1RIBOSOMAL RNA METHYLTRANSFERASE0.96positive
g16762.t1YY1 ASSOCIATED PROTEIN-RELATED0.96positive
g19246.t1CYTOCHROME P450 FAMILY 46 SUBFAMILY A0.96positive
g5352.t1RETINOVIN-RELATED0.96positive
g986.t1UNCHARACTERIZED0.96positive
g16112.t1MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE0.96positive
g2392.t1IP22168P0.96positive
g28024.t1HSC70CB, ISOFORM G-RELATED0.96positive
g11102.t1CHARGED MULTIVESICULAR BODY PROTEIN0.96positive
g8841.t1LD33804P0.96positive
g6346.t1MERLIN/MOESIN/EZRIN/RADIXIN0.96positive
g11802.t1--0.96positive
g20711.t1HIGH-AFFINITY CHOLINE TRANSPORTER 10.96positive
g22384.t1SARCOGLYCANS0.96positive
g11025.t1ACID PHOSPHATASE-RELATED0.96positive
g368.t1--0.95positive
g5669.t1ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL0.95positive
g8345.t1PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE0.95positive
g3032.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.95positive
g3928.t1BEN DOMAIN-CONTAINING PROTEIN 30.95positive
g8783.t1CARBONIC ANHYDRASE0.95positive
g28924.t1--0.95positive
g6392.t1TBP-1 INTERACTING PROTEIN0.94positive
g13201.t1CYTOCHROME P450 FAMILY 40.94positive
g12932.t1--0.93positive
g27352.t1GLYCOSYL HYDROLASE0.92positive
g1538.t1--0.92positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 236 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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