Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g1599.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g1599.t1
Gene ID Description PCC Relationship
g1599.t1DYNACTIN 1-RELATED MICROTUBULE-BINDING1positive
g9207.t1--0.94positive
g20121.t1CARBOHYDRATE SULFOTRANSFERASE0.94positive
g3719.t1LIMBIN/ELLIS-VAN CREVELD PROTEIN0.93positive
g22811.t1ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE0.93positive
g16166.t1--0.92positive
g27954.t1DYNEIN HEAVY CHAIN0.92positive
g8802.t1--0.92positive
g22094.t1--0.92positive
g10792.t1--0.91positive
g30121.t1ANNEXIN0.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 27 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP