Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g16192.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g16192.t1
Gene ID Description PCC Relationship
g16192.t1--1positive
g18695.t1SYNTROPHIN0.97positive
g12698.t1TOPOISOMERASE II-ASSOCIATED PROTEIN PAT10.96positive
g1315.t1FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED0.96positive
g24302.t1--0.96positive
g12080.t1LYSINE-SPECIFIC DEMETHYLASE0.96positive
g6271.t1CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN0.96positive
g2388.t1HELICASE SRCAP-RELATED0.96positive
g659.t1--0.96positive
g2997.t1METHYL-CPG BINDING PROTEIN, DROSOPHILA0.95positive
g3318.t1--0.95positive
g29391.t1--0.95positive
g12187.t1--0.95positive
g16988.t1SERINE/THREONINE-PROTEIN KINASE TAO0.95positive
g27831.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.94positive
g8834.t1TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 40.94positive
g18444.t1TRANSCRIPTION FACTOR ONECUT0.94positive
g21307.t1PARP/ZINC FINGER CCCH TYPE DOMAIN CONTAINING PROTEIN0.94positive
g4495.t1--0.94positive
g32247.t1N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE0.93positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 85 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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