Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g16252.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g16252.t1
Gene ID Description PCC Relationship
g16252.t1TYROSINE-PROTEIN KINASE RECEPTOR1positive
g27928.t1--0.93positive
g22184.t1--0.93positive
g31947.t1ENDONUCLEASE-RELATED0.92positive
g11148.t1--0.91positive
g33541.t1--0.86positive
g18808.t1L1 TRANSPOSABLE ELEMENT-RELATED0.86positive
g10263.t1--0.86positive
g10896.t1-0.86positive
g1259.t1--0.86positive
g13279.t1--0.86positive
g14599.t1--0.86positive
g15717.t1--0.86positive
g16671.t1--0.86positive
g16909.t1--0.86positive
g17566.t1KERATIN, ULTRA HIGH-SULFUR MATRIX PROTEIN-LIKE0.86positive
g1790.t1PULMONARY SURFACTANT-ASSOCIATED PROTEIN A0.86positive
g18687.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.86positive
g18792.t1--0.86positive
g18796.t1INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN0.86positive
g19439.t1REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN0.86positive
g19534.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.86positive
g19535.t1--0.86positive
g19599.t1PROTEIN SIDEKICK0.86positive
g20047.t1SIMILAR TO RIKEN CDNA E130308A190.86positive
g21064.t1PROTEIN CBG266940.86positive
g23109.t1RETROTRANSPOSON0.86positive
g24491.t1GAG-RELATED PROTEIN0.86positive
g25912.t1--0.86positive
g26884.t1--0.86positive
g27516.t1--0.86positive
g27779.t1--0.86positive
g28629.t1SI:CH211-108C17.2-RELATED-RELATED0.86positive
g29592.t1--0.86positive
g29843.t1--0.86positive
g31225.t1--0.86positive
g31322.t1--0.86positive
g31374.t1--0.86positive
g32239.t1--0.86positive
g33113.t1PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN0.86positive
g33555.t1--0.86positive
g33562.t1RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN0.86positive
g33612.t1--0.86positive
g34010.t1LIPOXYGENASE0.86positive
g34259.t1APPLE DOMAIN-CONTAINING PROTEIN0.86positive
g35700.t1--0.86positive
g36055.t1--0.86positive
g36292.t1--0.86positive
g36602.t1--0.86positive
g3906.t1--0.86positive
g4137.t1--0.86positive
g4256.t1--0.86positive
g7457.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.86positive
g8211.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.86positive
g8246.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.86positive
g8924.t1--0.86positive
g9204.t1--0.86positive
g31652.t1--0.85positive
g24075.t1--0.85positive
g7144.t1--0.84positive
g16739.t1--0.83positive
g30763.t1--0.80positive
g89.t1INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED0.80positive
g24035.t1DUF3504 DOMAIN-CONTAINING PROTEIN0.79positive
g4564.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.74positive
g12934.t1--0.72positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 1571 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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