Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g16689.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g16689.t1
Note: a hub gene can be co-expressed with thousands of genes, so each query gene is limited to its 100 strongest partners (positive and negative counted separately). Both the networks above and the table below show only those — this is not the complete network of the query genes.
Gene ID Description PCC Relationship
g16689.t1RETROTRANSPOSON1positive
g26559.t1PROTEIN CBG266940.96positive
g89.t1INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED0.94positive
g31652.t1--0.94positive
g34816.t1ALPHA-MANNOSIDE BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE0.90positive
g31261.t1--0.89positive
g10094.t1--0.89positive
g10673.t1--0.89positive
g1120.t1RETROTRANSPOSON0.89positive
g11752.t1--0.89positive
g12077.t1MYOSIN LIGHT CHAIN 1, 30.89positive
g12537.t1TESTICULAR SOLUBLE ADENYLYL CYCLASE0.89positive
g13469.t1--0.89positive
g1396.t1--0.89positive
g14051.t1--0.89positive
g14817.t1--0.89positive
g14963.t1--0.89positive
g15443.t1--0.89positive
g15532.t1UNCHARACTERIZED0.89positive
g16709.t1--0.89positive
g16956.t1RETROTRANSPOSON0.89positive
g17036.t1--0.89positive
g17197.t1PROTEIN CBG266940.89positive
g17841.t1PROTEIN CBG266940.89positive
g18235.t1--0.89positive
g19041.t1--0.89positive
g19354.t1--0.89positive
g19499.t1--0.89positive
g19641.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.89positive
g20020.t1--0.89positive
g20073.t1--0.89positive
g20162.t1--0.89positive
g20163.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.89positive
g20481.t1TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)0.89positive
g20778.t1--0.89positive
g21040.t1--0.89positive
g21364.t1RETROTRANSPOSON0.89positive
g21400.t1--0.89positive
g21676.t1--0.89positive
g22399.t1ULP_PROTEASE DOMAIN-CONTAINING PROTEIN0.89positive
g22737.t1REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN0.89positive
g23075.t1--0.89positive
g23101.t1--0.89positive
g23260.t1--0.89positive
g23529.t1DNA HELICASE RECQ FAMILY MEMBER0.89positive
g23566.t1CARBOHYDRATE SULFOTRANSFERASE0.89positive
g24359.t1TYROSINE-PROTEIN KINASE RECEPTOR0.89positive
g24561.t1--0.89positive
g24644.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.89positive
g24749.t1--0.89positive
g24795.t1MOLTING PROTEIN MLT-40.89positive
g25313.t1PROTEIN CBG238060.89positive
g25375.t1CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED0.89positive
g25731.t1APPLE DOMAIN-CONTAINING PROTEIN0.89positive
g25789.t1REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN0.89positive
g26099.t1--0.89positive
g26182.t1--0.89positive
g26374.t1--0.89positive
g26638.t1RETROTRANSPOSON0.89positive
g27946.t1--0.89positive
g28099.t1--0.89positive
g28519.t1CELL FATE DETERMINING PROTEIN MAB21-RELATED0.89positive
g29025.t1--0.89positive
g29245.t1--0.89positive
g29257.t1--0.89positive
g29315.t1PROTEIN CBG266940.89positive
g29390.t1ATP-DEPENDENT DNA HELICASE0.89positive
g29646.t1--0.89positive
g29705.t1BETA TRANSDUCIN-RELATED PROTEIN0.89positive
g30246.t1-0.89positive
g30589.t1OTU DOMAIN CONTAINING PROTEIN0.89positive
g31099.t1--0.89positive
g32050.t1--0.89positive
g32609.t1--0.89positive
g32744.t1--0.89positive
g3289.t1--0.89positive
g32991.t1--0.89positive
g33134.t1-0.89positive
g33219.t1--0.89positive
g33890.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN0.89positive
g3395.t1--0.89positive
g34282.t1--0.89positive
g34755.t1THREE PRIME REPAIR EXONUCLEASE 1, 20.89positive
g35130.t1ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN-RELATED0.89positive
g35326.t1SI:CH211-108C17.2-RELATED-RELATED0.89positive
g35703.t1--0.89positive
g36265.t1--0.89positive
g36589.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.89positive
g4333.t1--0.89positive
g5127.t1--0.89positive
g5971.t1--0.89positive
g6147.t1PROTEIN CBG266940.89positive
g6299.t1PHD-TYPE DOMAIN-CONTAINING PROTEIN0.89positive
g6542.t1FLAP ENDONUCLEASE FAMILY MEMBER0.89positive
g6615.t1--0.89positive
g7009.t1PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 40.89positive
g7460.t1THAP DOMAIN PROTEIN0.89positive
g7687.t1PROTEIN CBG266940.89positive
g7851.t1--0.89positive
g8295.t1CXC DOMAIN-CONTAINING PROTEIN-RELATED0.89positive
g8849.t1--0.89positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 4852 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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