Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g16730.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g16730.t1
Gene ID Description PCC Relationship
g16730.t1PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC11positive
g12970.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.98positive
g3316.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED0.97positive
g16657.t1RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE0.97positive
g12287.t1NETRIN/LAMININ-RELATED0.96positive
g26432.t1--0.96positive
g13790.t1ANGIOTENSIN-CONVERTING ENZYME0.96positive
g10502.t1POTASSIUM/PROTON ANTIPORTER-RELATED0.96positive
g10812.t1PERIOSTIN-RELATED0.96positive
g23615.t1POLY A POLYMERASE0.96positive
g6524.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.95positive
g18490.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.95positive
g7552.t1RHO-TYPE GTPASE ACTIVATING PROTEIN0.95positive
g601.t1TETRATRICOPEPTIDE REPEAT PROTEIN 130.95positive
g12735.t1GOLGI MEMBRANE PROTEIN YIP10.94positive
g12582.t1NUCLEOREDOXIN0.94positive
g9772.t1COLLAGEN ALPHA0.94positive
g17408.t1UNCHARACTERIZED0.94positive
g34163.t1--0.94positive
g8461.t1--0.94positive
g9273.t1TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED0.94positive
g35028.t1T-BOX PROTEIN-RELATED0.94positive
g30458.t1SODIUM/CHLORIDE DEPENDENT TRANSPORTER0.94positive
g17188.t1UBIQUITINATION FACTOR E40.93positive
g4446.t1LUNG SEVEN TRANSMEMBRANE RECEPTOR0.93positive
g10302.t1SODIUM/DICARBOXYLATE SYMPORTER-RELATED0.91positive
g17263.t1--0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 113 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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