Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g16902.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g16902.t1
Gene ID Description PCC Relationship
g16902.t1IONOTROPIC GLUTAMATE RECEPTOR1positive
g27945.t1--0.99positive
g18965.t1CARBOHYDRATE SULFOTRANSFERASE0.99positive
g17098.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g11889.t1PROSTAGLANDIN G/H SYNTHASE0.99positive
g27864.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g3364.t1GUANYLYL CYCLASE0.99positive
g528.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.99positive
g5016.t1ADENYLATE CYCLASE TYPE 10.99positive
g23600.t1G PROTEIN-COUPLED RECEPTOR0.99positive
g12791.t1SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN0.99positive
g18961.t1G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER0.99positive
g35342.t1BRORIN FAMILY MEMBER0.99positive
g10112.t1CENTROSOMAL PROTEIN 20.99positive
g14637.t1APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR.0.99positive
g4257.t1CRYPTOCHROME0.99positive
g19669.t1NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g26779.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g16164.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g15545.t1--0.99positive
g7906.t1POLYCYSTIN FAMILY MEMBER0.99positive
g28228.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g562.t1VOLTAGE-GATED POTASSIUM CHANNEL0.99positive
g9043.t1METAXIN RELATED0.99positive
g1797.t1DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE0.99positive
g4265.t1SYNAPTOTAGMIN0.99positive
g29503.t1ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 600.99positive
g19186.t1TNF RECEPTOR ASSOCIATED FACTOR0.99positive
g21558.t1I[[H]] CHANNEL, ISOFORM E0.99positive
g16807.t1--0.99positive
g14021.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g498.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g35364.t1--0.99positive
g1847.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g29047.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g1846.t1--0.99positive
g4437.t1--0.99positive
g29914.t1BETA-1,4-GALACTOSYLTRANSFERASE0.99positive
g11811.t1B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR0.99positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 234 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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