Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g17021.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g17021.t1
Gene ID Description PCC Relationship
g17021.t1CYSTEINE-RICH PDZ-BINDING PROTEIN1positive
g2026.t1DNAJ HOMOLOG SUBFAMILY B MEMBER 20.95positive
g8380.t1UNCHARACTERIZED0.94positive
g5760.t1--0.94positive
g22437.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED0.94positive
g5530.t1RHOPHILIN0.93positive
g31071.t1POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 30.93positive
g3275.t1--0.93positive
g7058.t1PROTEIN FAM181B0.93positive
g23968.t1RAS-RELATED PROTEIN RAB0.93positive
g27602.t1ACROSIN-RELATED0.93positive
g1305.t1ABC TRANSPORTER G FAMILY MEMBER 280.93positive
g14216.t1SCD6 PROTEIN-RELATED0.92positive
g15840.t1TNF RECEPTOR ASSOCIATED FACTOR0.92positive
g10540.t1SMALL INTEGRAL MEMBRANE PROTEIN 120.92positive
g1121.t1CHARGED MULTIVESICULAR BODY PROTEIN0.92positive
g428.t1DET1- AND DDB1-ASSOCIATED PROTEIN 10.92positive
g15967.t1CULLIN0.92positive
g10690.t1--0.91positive
g517.t1PHOSPHOLIPID SCRAMBLASE-RELATED0.91positive
g9971.t1CHARGED MULTIVESICULAR BODY PROTEIN0.90positive
g15719.t1PYRIDOXAL 5'-PHOSPHATE SYNTHASE SUBUNIT SNZ1-RELATED0.90positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 87 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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