Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g17387.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g17387.t1
Gene ID Description PCC Relationship
g17387.t1--1positive
g6623.t1ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 20.95positive
g3887.t1F-BOX ONLY PROTEIN 150.94positive
g22684.t1BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA20.93positive
g16775.t1SHC TRANSFORMING PROTEIN0.93positive
g23794.t1ALPHA CATENIN0.93positive
g8971.t1--0.93positive
g27347.t1PROTEIN CBG162000.93positive
g28145.t1SPECKLE-TYPE POZ PROTEIN0.93positive
g7240.t1--0.92positive
g28413.t1--0.92positive
g10581.t150S RIBOSOMAL PROTEIN L30.92positive
g29995.t1CAMK FAMILY PROTEIN KINASE0.92positive
g13338.t1HERMANSKY-PUDLAK SYNDROME 3 PROTEIN0.92positive
g28219.t1--0.92positive
g34827.t1UNCHARACTERIZED PROTEIN KIAA20130.92positive
g25555.t1CULLIN0.92positive
g27968.t1RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS0.92positive
g11627.t1CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED0.91positive
g34859.t1DEAD-BOX ATP-DEPENDENT RNA HELICASE 500.91positive
g32426.t1--0.90positive
g4207.t1BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN0.90positive
g9045.t1DED DOMAIN-CONTAINING PROTEIN0.84positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 61 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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