Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g18403.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g18403.t1
Gene ID Description PCC Relationship
g18403.t1BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC71positive
g5285.t1SERINE/THREONINE PROTEIN PHOSPHATASE0.97positive
g32280.t1CYCLIN D1-BINDING PROTEIN 10.96positive
g66.t1PATCHED-RELATED0.96positive
g12008.t1--0.96positive
g22700.t1SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN0.96positive
g27714.t1--0.96positive
g4054.t1SORTING NEXIN0.96positive
g7052.t1RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING0.96positive
g35281.t1E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED0.96positive
g3116.t1UNCHARACTERIZED0.96positive
g13218.t1RAB GTPASE-ACTIVATING PROTEIN 1-LIKE0.96positive
g29357.t1SIDEROFLEXIN0.95positive
g2803.t1IP01015P-RELATED0.95positive
g4703.t1--0.95positive
g22814.t1RIKEN CDNA 6820408C150.95positive
g15522.t1RIBONUCLEASE H2 SUBUNIT B0.95positive
g8887.t1ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 100.95positive
g22283.t1--0.95positive
g29451.t1--0.94positive
g10814.t1DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED0.94positive
g10453.t1--0.92positive
g35861.t1DNA HELICASE RECQ FAMILY MEMBER0.91positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 87 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP