Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g18490.t1
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g18490.t1
Gene ID Description PCC Relationship
g18490.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN1positive
g12735.t1GOLGI MEMBRANE PROTEIN YIP10.98positive
g27840.t1POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE0.96positive
g12274.t1ATP-CITRATE SYNTHASE0.96positive
g7552.t1RHO-TYPE GTPASE ACTIVATING PROTEIN0.96positive
g27783.t1SI:DKEY-19B23.12-RELATED0.96positive
g12287.t1NETRIN/LAMININ-RELATED0.96positive
g8569.t1PROTEIN ABHD14B-LIKE0.96positive
g19335.t1UNCHARACTERIZED0.96positive
g18266.t1TRANSCRIPTION ELONGATION FACTOR SPT60.95positive
g27740.t1DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED0.95positive
g14195.t1V-TYPE ATP SYNTHASE SUBUNIT D0.95positive
g16730.t1PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC10.95positive
g12582.t1NUCLEOREDOXIN0.95positive
g2245.t1PROTEIN UNC-50 HOMOLOG0.95positive
g3316.t1EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED0.95positive
g16765.t1PHOSPHATIDYLCHOLINE TRANSFER PROTEIN0.94positive
g35047.t1GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN0.94positive
g12970.t1TRANSMEMBRANE 9 SUPERFAMILY PROTEIN0.94positive
g3592.t1SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA0.94positive
g32416.t1COILED-COIL DOMAIN-CONTAINING PROTEIN 1580.94positive
g18319.t1D-AMINO ACID OXIDASE0.94positive
g3327.t1-0.94positive
g15047.t1ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN0.93positive
g2560.t1VOLTAGE-GATED POTASSIUM CHANNEL0.91positive
g9715.t1--0.87positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 107 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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