Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g18961.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g18961.t1
Gene ID Description PCC Relationship
g18961.t1G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER1positive
g35342.t1BRORIN FAMILY MEMBER1.00positive
g16163.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 131.00positive
g26779.t15-HYDROXYTRYPTAMINE RECEPTOR1.00positive
g15545.t1--1.00positive
g23600.t1G PROTEIN-COUPLED RECEPTOR0.99positive
g11889.t1PROSTAGLANDIN G/H SYNTHASE0.99positive
g15439.t1--0.99positive
g4434.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.99positive
g528.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.99positive
g7283.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g10642.t1COLLAGEN ALPHA0.99positive
g16902.t1IONOTROPIC GLUTAMATE RECEPTOR0.99positive
g28228.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g14626.t1ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA0.99positive
g5016.t1ADENYLATE CYCLASE TYPE 10.99positive
g7546.t1--0.99positive
g10112.t1CENTROSOMAL PROTEIN 20.99positive
g27084.t1RADIAL SPOKE HEAD 1 HOMOLOG0.99positive
g10672.t1--0.99positive
g4055.t1--0.99positive
g32030.t1TRANSMEMBRANE PROTEIN 1630.99positive
g12437.t1SOLUTE CARRIER FAMILY 20.99positive
g7906.t1POLYCYSTIN FAMILY MEMBER0.99positive
g16164.t1TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 130.99positive
g3364.t1GUANYLYL CYCLASE0.99positive
g31603.t1--0.99positive
g438.t1PR DOMAIN ZINC FINGER PROTEIN0.99positive
g9610.t1--0.99positive
g29662.t1RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 10.99positive
g17731.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g1988.t1HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR0.99positive
g27742.t1--0.99positive
g18965.t1CARBOHYDRATE SULFOTRANSFERASE0.99positive
g17621.t1--0.99positive
g28319.t1CYSTEINE-RICH SECRETORY PROTEIN-RELATED0.99positive
g12064.t1SAM DOMAIN-CONTAINING PROTEIN-RELATED0.99positive
g10484.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g28123.t1POTASSIUM CHANNEL, SUBFAMILY K0.99positive
g28006.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g1470.t1--0.98positive
g3880.t1STAR-RELATED LIPID TRANSFER PROTEIN 90.98positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 245 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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