Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g18965.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g18965.t1
Gene ID Description PCC Relationship
g18965.t1CARBOHYDRATE SULFOTRANSFERASE1positive
g16902.t1IONOTROPIC GLUTAMATE RECEPTOR0.99positive
g10112.t1CENTROSOMAL PROTEIN 20.99positive
g27945.t1--0.99positive
g27864.t1TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS0.99positive
g528.t1FCH AND DOUBLE SH3 DOMAINS PROTEIN0.99positive
g4055.t1--0.99positive
g12791.t1SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN0.99positive
g29471.t1PROLYL 4-HYDROXYLASE ALPHA SUBUNIT0.99positive
g2642.t1SRCR DOMAIN-CONTAINING PROTEIN0.99positive
g9043.t1METAXIN RELATED0.99positive
g31167.t1LD44762P0.99positive
g3364.t1GUANYLYL CYCLASE0.99positive
g4434.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.99positive
g4265.t1SYNAPTOTAGMIN0.99positive
g15545.t1--0.99positive
g11889.t1PROSTAGLANDIN G/H SYNTHASE0.99positive
g5256.t1OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR0.99positive
g16362.t1KELCH PROTEIN0.99positive
g18961.t1G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER0.99positive
g16653.t1CALCIUM BINDING PROTEIN0.99positive
g3365.t1--0.99positive
g3925.t1UBIQUITIN-PROTEIN LIGASE E3C0.99positive
g8334.t1--0.99positive
g12092.t1RIBULOKINASE0.99positive
g7527.t1--0.99positive
g7147.t1KREMEN PROTEIN0.99positive
g29047.t15-HYDROXYTRYPTAMINE RECEPTOR0.99positive
g27588.t1MYOTROPHIN0.99positive
g17486.t1--0.99positive
g16807.t1--0.99positive
g32539.t1--0.99positive
g12097.t1--0.99positive
g19981.t1CYCLIC NUCLEOTIDE PHOSPHODIESTERASE0.99positive
g27471.t1--0.99positive
g4367.t1WDR41-RELATED0.98positive
g21221.t1INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP60.98positive
g30091.t1SULFOTRANSFERASE SULT0.98positive
g14132.t1TRANSCRIPTIONAL REPRESSOR PROTEIN YY0.98positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 170 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
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