Co-expression Network Analysis

Interactive visualization of gene co-expression networks, expression and funtional enrichment analysis.

📊 Global Network of g192.t1
Co-expression Network View
Network Legend
Yellow: Query proteins
Green: Interaction proteins
Pink line: Own interaction + positive co-expression
Blue line: Own interaction + negative co-expression
Node size reflects how many connections the gene has (hubs are drawn larger). Hover any node to see the annotation of the gene it stands for (PANTHER / InterPro / GO description, or NR when the others are absent) and a link to its gene page.
📋 View Detailed Network Information
Co-expressed Genes of g192.t1
Gene ID Description PCC Relationship
g192.t1COLLAGEN ALPHA1positive
g7283.t1AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED0.99positive
g33383.t1IP13529P0.99positive
g7.t1NEUROTRANSMITTER GATED ION CHANNEL0.99positive
g6445.t1FIBRILLIN-RELATED0.99positive
g27514.t1TRANSLATION ELONGATION FACTOR-RELATED0.99positive
g25713.t1--0.99positive
g13536.t1SODIUM/CALCIUM EXCHANGER0.99positive
g14669.t1COLLAGEN ALPHA0.99positive
g113.t1DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING0.99positive
g10390.t1--0.99positive
g6446.t1ENDOGLIN/TGF-BETA RECEPTOR TYPE III0.99positive
g4327.t1TYROSINE-PROTEIN KINASE RECEPTOR0.99positive
g12614.t1BONUS, ISOFORM C-RELATED0.99positive
g14564.t1RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 10.99positive
g15439.t1--0.99positive
g27468.t1SOLUTE CARRIER FAMILY 22 MEMBER0.99positive
g5747.t1ATAXIA TELANGIECTASIA MUTATED ATM -RELATED0.99positive
g24840.t1--0.99positive
g27623.t1SERINE PROTEASE0.99positive
g12486.t1GLIAL CELLS MISSING RELATED/GLIDE0.99positive
g3925.t1UBIQUITIN-PROTEIN LIGASE E3C0.99positive
g14023.t1LYSYL OXIDASE-LIKE-RELATED0.99positive
g4326.t1FIBROBLAST GROWTH FACTOR RECEPTOR0.99positive
g2113.t1--0.99positive
g28150.t1--0.99positive
g19151.t1VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM0.99positive
g12437.t1SOLUTE CARRIER FAMILY 20.99positive
g27084.t1RADIAL SPOKE HEAD 1 HOMOLOG0.99positive
g14393.t1COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING0.99positive
g6844.t1PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED0.99positive
g3350.t1CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN0.99positive
g27014.t1CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A0.99positive
g32030.t1TRANSMEMBRANE PROTEIN 1630.99positive
g520.t1VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED0.99positive
g1642.t1KELCH PROTEIN0.99positive
g5941.t1PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED0.99positive
g16491.t1NADH-CYTOCHROME B5 REDUCTASE0.99positive
g17699.t1G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE0.99positive
g7800.t1GLUTAMATE SEMIALDEHYDE DEHYDROGENASE0.99positive
g30478.t1--0.99positive
g1938.t1LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED0.99positive
g17411.t1PROTEASE M14 CARBOXYPEPTIDASE0.99positive
g26571.t1--0.99positive
g14949.t1--0.99positive
g3647.t1UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN0.99positive
g22989.t1--0.99positive
g34672.t1COLLAGEN ALPHA0.99positive
g32616.t1OS06G0237300 PROTEIN0.99positive
g24689.t1FIBRINOGEN/TENASCIN/ANGIOPOEITIN0.98positive
g6840.t1--0.98positive
g27335.t1--0.98positive
g30185.t1TYROSINE-PROTEIN KINASE RECEPTOR0.97positive
Further Analysis for Network Members
Next Step: Dynamic Expression View

What this does. Everything above treats every gene the same way. Dynamic Expression View redraws this same network but colours each node by how much that gene changes between two conditions, so you can see which part of the network responds. It needs one input the network itself does not carry: a per-gene expression ratio.

Where the ratio comes from. CnidoSite holds an RNA-seq expression matrix for this species, so the ratio can be built here rather than elsewhere: pick the samples for each side of your comparison and every gene gets log2((mean of group A + 1) / (mean of group B + 1)). This network has 362 gene pairs and one run of Dynamic Expression View draws at most 10, so the button below carries the 10 with the strongest |PCC|.

Gene pairs carried over (10)
Opens the ratio builder with these pairs already loaded. It computes the ratios, then hands both the pairs and the ratios to the network view in one step.
Or take the pairs by hand
Click to select all, then paste into step 2 of Dynamic Expression View as GeneA GeneB, one pair per line. Its step 3 still needs the expression ratios.
TOP